Rare disease

Crohn's disease

Monoclonal antibodies

【Product name】IILARIS, ADCETRIS, Muromonab

[English common name]Monoclonal antibody

[Chinese common name]Monoclonal antibodies

[English name]

[Chinese other name]

[indications]
Iodine [131I] tumor cell nuclear human mouse chimeric monoclonal antibody injection: for the late stage of radiotherapy and chemotherapy can not control or relapseLung cancerRadioimmunotherapy.
Recombinant anti-CD25 humanized monoclonal antibody injection: This product is suitable for preventing the occurrence of acute rejection after renal transplantation, and can be combined with an immunosuppressive regimen containing a calmodulin inhibitor and corticosteroids.

【Dosage】
Iodine [131I] tumor cell nuclear human mouse chimeric monoclonal antibody injection:
1. Medication method:
(1) Systemic administration: This product can be directly bolused, or intravenously established with saline to make a bolus or instillation.
(2) Topical administration: The drug is injected into the tumor by pulmonary puncture under imaging guidance (CT, fluoroscopy or DSA).
2. Dosage: Two times per course of treatment, with an interval of 2-4 weeks. The specific dosage is:
(1) Systemic intravenous injection: The dose is 29.6 MBq (0.8 mCi)/kg.
(2) Topical administration: Each dose was 18.5-37.0 MBq (0.5-1 mCi)/cm3 of tumor, and the maximum dose was 1850 MBq (50 mCi).
Recombinant anti-CD25 humanized monoclonal antibody injection: the recommended dose is 1mg/kg, diluted to 50mL of 0.9% sodium chloride injection before use, and then intravenously infused, 15 minutes after the end. The first dose should be administered within 24 hours prior to transplantation, and then administered once every 14 days, twice for a course of treatment. This product can not be directly injected, but should be diluted with 50% of 0.9% sodium chloride injection before intravenous administration. Do not violently oscillate when mixing the solution and gently flip it to prevent foaming. Since this product does not contain any preservatives or bacteriostatic agents, it must be carefully stored to ensure the solution is sterile. This product is a colorless liquid contained in a disposable bottle. Any unused parts after opening should be discarded. Do not dilute and infuse with other drugs in the same solution.

[Storage]
Iodine [131I] tumor cell nuclear human mouse chimeric monoclonal antibody injection: sealed, shading, and stored in a dry place.
Recombinant anti-CD25 humanized monoclonal antibody injection: stored and transported at 2-8 ° C in the dark. Do not freeze or shake vigorously. After dilution, the drug solution can be stored at 2-8 ° C for 24 hours and at room temperature for 4 hours.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
Crohn's disease

BCG

【Product name】IMMUCYST, Immunobladder, TICE BCG

[English common name]Bacillus Calmette-Guerin vaccine

[Chinese common name]BCG

[English name]

[Chinese other name]

[Indications] This product (BCG immunotherapeutic agent) is suitable for intravesical use and treatment of primary recurrent carcinoma in situ (CIS) of the bladder to reduce the frequency of tumor recurrence. It is indicated for the treatment of carcinoma in situ with or without papillary tumors. However, it is not suitable for the treatment of papilloma that occurs alone. This product is also used as a remedy for the bladder to respond to other in situ carcinoma (CIS) treatments. Treatment and prevention of primary or recurrent carcinoma in situ or superficial papilloma after transurethral resection (TA and T1).

[Usage and Dosage] Intravesical treatment and prevention of bladder carcinoma in situ (CIS) should be started 7 to 14 days after biopsy or transurethral resection. In a single dose of 3 vials, this product (BCG immunotherapeutic agent) was administered by intravesical injection once a week for 6 weeks (induction therapy). Each dose (3 bottles of prepared vials) was diluted with 50 ml of bacteria and diluted with preservative-free saline to a total of 53 ml. The urethral catheter is inserted into the bladder under aseptic conditions, guiding the contents of the bladder, and then slowly injecting 50 ml of the suspension of the product by gravity, and then taking out the catheter. During the first hour after perfusion, the patient should be placed in the prone, lying down and lying on the left and right sides for 15 minutes. The patient can then stand but maintain the suspension for 60 minutes for a total of 2 hours. It should be taught to urinate if needed for less time. . At the end of the 2 hours, all patients urinate in a sitting position for safety reasons. Patients should be taught to maintain adequate water. The true number of perfusions required to achieve the optimal response is still unknown. Most responding patients are achieved with 6 to 12 perfusions.

[Storage] The medicine should be placed in a refrigerator of 2 to 8 degrees Celsius (not frozen); if it deteriorates or expires, it can no longer be used.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
Bullous epidermolysis

Captopril

【Product name】CAPTORIL-R, Capoten

[English common name]Captopril

[Chinese common name]Captopril

[English name]

[Chinese other name]

[indications]
Captopril Dropping Pills: This product is suitable for high blood pressure and heart failure.
Captopril capsule: This product is suitable for high blood pressure and heart failure.
Compound captopril tablets: the main effect of this product
1. Hypertension, can be used alone or in combination with other antihypertensive drugs.
2. Heart failure, can be used alone or in combination with cardiac diuretics.

【Dosage】
Captopril Dropping Pills: This product should be applied under the guidance or supervision of a physician.
Captopril capsules:
1. Slow intravenous injection. An adult 25 mg in 20 ml of 10% glucose solution was administered slowly, intravenously (10 minutes), followed by intravenous injection of 50 mg of 10 ml of 10% glucose solution for 1 hour.
2. Depending on the condition or individual differences. This product should be applied under the guidance or supervision of the physician. The dosage should be adjusted according to the individualization principle and adjusted according to the curative effect.
Compound captopril tablets: depending on the condition or individual differences. This product should be taken under the guidance or supervision of a physician. The dosage should be adjusted according to the individualization principle and adjusted according to the curative effect.
1. The amount of adult use:
(1) High blood pressure, 12.5mg once a day, 2-3 times a day, increase to 50mg within 1-2 weeks as needed, 2-3 times a day, other antihypertensive drugs can be added when the effect is still not satisfactory.
(2) Heart failure, start oral administration of 12.5mg 2-3 times a day, gradually increase to 50mg if necessary, 2-3 times a day. If further dosage is needed, it should be considered after 2 weeks of treatment; For patients taking diuretics at low sodium/low blood volume and normal or low blood pressure, the initial dose should be 6.25 mg 3 times a day, and then gradually increased to the usual amount by testing.

[Storage]
Captopril Dropping Pills: Sealed and placed in a cool place.
Captopril capsules: sealed and placed in a cool place.
Compound captopril tablets: shading, sealed, and stored in a dry place below 30 °C.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
Early onset Parkinson's disease

Carbidoba

【Product name】Duopa, Carbidopa and Levodopa, Larodopa, Lodosyn, Sinemet

[English common name]Carbidopa

[Chinese common name]Carbidoba

[English name]alpha-Methyldopahydrazine, Benzenepropanoic acid, Carbidopa

[Chinese other name]Carbidopa, Kabedoba, Shiraz

[indications]
Carbidopa / levodopa tablets: This product is used forParkinsonDisease, symptomatic Parkinson's syndrome (arteriosclerosis or toxicity after encephalitis), but does not include Parkinson's syndrome caused by drugs.
Compound carbidopa tablets: This product is used for Parkinson's disease, symptomatic Parkinson's syndrome (arteriosclerosis or toxicity after encephalitis), but does not include Parkinson's syndrome caused by drugs.
Carbidopa tablets: in combination with levodopa, forParkinson's DiseaseAnd Parkinson's syndrome.

【Dosage】
Carbidopa / levodopa tablets: Oral: start 137.5mg each time, 3 times a day, increase 137.5mg daily, until 2.2g per day. The maintenance dose is 550 mg per day for 20 to 40 weeks. Controlled-release tablets: mild to moderate patients, starting dose of 250mg each time, 2 to 3 times a day, gradually increasing the dose, most patients only need 2 to 8 tablets per day, taking fractions. Levodopa was discontinued 8 hours prior to the start of dosing.
Compound carbidopa tablets: The optimal dose for taking this product should be determined by the doctor according to the patient's condition. Commonly used amount: one and a half tablets at the beginning of oral administration, 3 times a day. After taking a week, according to the condition, every 3–4 days, half a day, until the best results. In patients with levodopa tablets, if you change this product, you should stop taking levodopa tablets for at least 12 hours. The initial dose administered is calculated as levodopa and should be equivalent to 25% of the original single dose. The maximum daily dose should not exceed 8 tablets (taken 4 times, 2 tablets each time).
Carbidopa tablets: 10 mg once orally, 3 to 4 times a day. The daily dose is gradually increased every 1 to 2 days, and the maximum dose can reach 100 mg per day.

[Storage]
Carbidopa / levodopa tablets: sealed.
Compound Carbidopa tablets: sealed.
Carbidopa tablets: shading, sealed and preserved.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
Parkinson , Acromegaly

Cameron

【Product name】Dostinex, CABASER

[English common name]Cabergoline

[Chinese common name]Cameron

[English name]1-[(6-Allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)-propyl]-3-ethylurea

[Chinese other name]6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl) ergoline-8-carboxamide

[indications]
For treatmentParkinson's Disease.
2. forHyperprolactinemia.
3. Try to useBreast cancer.

[Usage and Dosage] Usage and dosage of different indications:
Inhibition of physiological lactation: Adult: 1 mg, one-time administration on the first day after delivery. Liver damage: Adjust the dose.
Inhibition of lactation: Adult: 250mcg / 12 hours for 2 days.
Hyperprolactinemia-related diseases:
Adult: initial dose: 500mcg / week, and then according to the reaction, add 500mcg per month, can be administered once a week or twice a day on different days; more than 1mg should be administered in divided doses.
Conventional dose: 1 mg / week, up to: 4.5 mg / week. Take it at mealtime or after a meal.

[Storage]The storage of commercial tablets should be controlled at room temperature (20 to 25 ° C, 68 to 77 ° F).

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
Lennox-Gastaut syndrome , epilepsy

Lufinamide

【Product name】BANZEL

[English common name]Rufinamide

[Chinese common name]Lufinamide

[English name]

[Chinese other name]

Indications syndromeepilepsyAdjuvant therapy for seizures.

[Usage and Dosage] Initially 400-800mg per day, increase by 400-800mg / day every other day, reaching the goal of 3200mg / day. Avoid sudden stops (25% reduction every 2 days).

[Storage] Store tablets at 25 ° C (77 ° F); allow for offset 15 ° -30 ° C (59 ° F – 86 ° F). Moisture proof. Replace the cover after opening.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
Hereditary angioedema

Dechloramphenicol

【Product name】Decloxizine

[English common name]Decloxizine

[Chinese common name]Dechloramphenicol

[English name]Piperazine

[Chinese other name]Champyloxazine

[indications]
Dehydrochloride tablets for allergic diseases such as acute and chronic urticaria.
Compound hydroxypropyl theophylline dechlorsamine capsule: suitable forasthma, cough caused by bronchitis.

【Dosage】
Dehydrochloride tablets: Oral, 25-50 mg once a day, 3 times a day.
Compound hydroxypropyl theophylline dechlorpromazine capsule:
1. For the first time taking this product, the first dose must be 1 capsule, 3 times a day, and should be taken after normal use.
2, take 1-2 capsules at the onset of symptoms, 3-4 times a day, 1 capsule each time.
3. Take 1-2 capsules a day after the symptoms are relieved.
4, for the prevention of nighttime attacks, you can take 1-2 capsules before going to sleep.
5, if the medical history is longer, the patient with severe disease can increase the dose, 1 to 2 capsules each time, 3 to 4 times a day; after the symptom is relieved, it will be changed to 1 capsule per day, 3 times a day, or as directed by a doctor. .
6, children 1/3-1/2 tablets each time, 3-4 times a day, or under the guidance of a doctor.

[Storage]
Dehydrochlorozine hydrochloride tablets: sealed and stored.
Compound hydroxypropyl theophylline dechlorpromazine capsule: shading, sealed and preserved.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
Thalassemia , Thalassemia

Deferoxamine

【Product name】Desferal

[English common name]Deferoxamine

[Chinese common name]Deferoxamine

[English name]Desferal; Deferrioxamine B, Desferrioxamine; desferrioxamine mesylate

[Chinese other name]Go to Tiemin, except Tie Ling

[Indications] The main component of this product is deferoxamine mesylate.

【Dosage】
1. Treatment of chronic iron load overload chelation The main purpose of young iron overload patients is to achieve iron balance and prevent hemosiderosis; for older patients, it is hoped to reach the negative balance of iron slowly. Reduce elevated iron storage and prevent its toxic effects.
2. Children and adult patients are advised to start treatment with this product after the first 10-20 transfusions or when serum ferritin levels have reached 100o ng/ml. Iron overload or excessive product may cause growth retardation. If a child under 3 years of age begins chelation therapy, the growth should be closely monitored and the average daily dose should not exceed 40 mg/kg body weight. The dosage arrangement and mode of administration should be individualized and adjusted during the course of treatment based on the severity of the iron load.

[Storage] Sealed and stored in a cool place.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
Thalassemia , Thalassemia

Deferiprone

【Product name】Austin, Ferriprox

[English common name]Deferiprone

[Chinese common name]Deferiprone

[English name]

[Chinese other name]

[Indications] for the treatment of tolerated or unwilling to accept the existing chelating agent treatment of excessive iron loadThalassemiapatient.

[Usage and Dosage] Deferiprone treatment dose of 25mg / kg body weight, oral, three times a day, daily dose of 75mg / kg body weight. It can be calculated in half-pieces. See the dose chart below for the dose per kilogram of body weight. Dosages above 100 mg/kg/day are not recommended as they may potentially increase the risk of adverse reactions.

[Storage] Store below 30 °C.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
scleroderma

Dipyridamole

【Product name】AGGRENOX, Persantine

[English common name]Dipyridamole

[Chinese common name]Dipyridamole

[English name]Diazimiol, Bimopido

[Chinese other name]Bipyrimidinol

[indications]
Dipyridamole tablets: This product is mainly used for anti-platelet aggregation and is used to prevent thrombosis.
Dipyridamole dispersible tablets: anti-platelet drugs, this product is used to prevent thromboembolic diseases.
Dipyridamole sustained release capsule: This product is used for the prevention and treatment of thromboembolic diseases, either alone or in combination with aspirin.

【Dosage】
Dipyridamole tablets: oral. 25 ~ 50mg (1 ~ 2 tablets), 3 times a day, served before meals. Or follow the doctor's advice.
Dipyridamole dispersible tablets:
1. Oral. 25 to 50 mg each time (1 to 2 tablets), 3 times a day.
2. Oral or dissolved in about 100mL of warm water to take, according to the doctor's advice.
Dipyridamole sustained-release capsules: Oral, 200mg once, twice a day.

[Storage]
Dipyridamole tablets: sealed.
Dipyridamole dispersible tablets: shading, sealed, and stored in a cool place (not more than 20 ° C).
Dipyridamole sustained-release capsules: shading, sealed, and stored in a cool place.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
Fragile X syndrome

Clonidine

【Product name】Clonidine Controlled-release Patches

[English common name]Clonidine

[Chinese common name]Clonidine

[English name]2-(2,6-dichloroanilino)-2-imidazolin

[Chinese other name]2-(2',6'-dichloroanilino)-2-imidazoline

[indications]
Clonidine patch: for hypertension.
Clonidine transdermal patch: for Tourette syndrome (sounding and multiple movement combined with tic disorder).

【Dosage】
Clonidine patch: Remove the product, remove the protective layer, and apply it to the skin without dry skin. Adult patients use a piece (2.5cm2) for the first time, and then adjust the area (decreased or increased) according to the blood pressure drop. If it has increased to three pieces (75cm2), it still has no effect, and the adverse reaction is obvious. . Use it for three days and switch to a new patch.
Clonidine Transdermal Patch: Usage:
1. Application site: Under the shoulder blade (preferred); upper chest; hairless intact skin such as the posterior mastoid or the upper arm. Replace the new patch with a new one to replace the skin, so as to reduce skin irritation.
2. Use steps:
(1) Wash the application site with clean water.
(2) Remove the product, remove the protective layer, and apply it to the cleaned and dried place. It is also used for light pressure to ensure that the patch adheres firmly.
(3) Replace every 7 days. Eating or not does not affect the application of this product.
(4) When replacing the old patch, fold the patch in half and discard it in places where children and animals cannot reach it to prevent humans and animals from eating.

[Storage]
Clonidine patch: shading, sealed storage.
Clonidine transdermal patch: sealed, placed in a cool place.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
scleroderma , Paroxysmal nocturnal hemoglobinuria

Dextran

【Product name】 INJECTAFER, LOW MOLECULAR DEXTRAN D INJECTION, INFED, DEXTRAN

[English common name]Dextranum

[Chinese common name]Dextran

[English name]

[Chinese other name]

[indications]
Low molecular weight dextran amino acid injection: for the treatment of patients with reduced blood volume with protein deficiency
Compound dextran 40 injection: acute hemorrhage, especially suitable for initial treatment of acute massive hemorrhage; surgical hypovolemic shock due to trauma, burn (hot) and hemorrhage; blood volume reduction during surgery: reduction in extracorporeal perfusion The risk of complications due to extracorporeal circulation.
Dextran 40 Glucose Injection: This product is suitable for:
1. Shock is used for shock and toxic shock caused by various causes such as blood loss, trauma and burns.
2. Prevention of postoperative venous thrombosis for limb replantation and vascular surgery to prevent postoperative thrombosis.
3. Vascular embolism is used for angina pectoris, cerebral thrombosis, insufficient blood supply to the brain, and thromboangiitis obliterans.
4. During extracorporeal circulation, replace part of the blood, pre-fill the artificial heart-lung machine, which not only saves blood but also improves circulation.
Dextran hypromellose eye drops: reduce discomfort such as burning and irritation caused by dry eyes, and protect the eye from irritation. Reduce eye discomfort caused by exposure to sand or sunlight.

【Dosage】
Low molecular weight dextran amino acid injection: intravenous drip. 500ml once a day, can be used continuously for 4 to 5 days or as directed by a doctor.
Compound dextran 40 injection: 500-1000 mL of this product is infused intravenously every adult, and the dosage should be adjusted according to the patient's age, clinical performance and body weight. The dose of the extracorporeal circulation solution is 20 to 30 mL/kg, and the dextran 40 is 2 to 3 g/kg.
Dextran 40 Glucose Injection:
1. Intravenous infusion, the dosage depends on the condition, the amount of adult commonly used is 250 ~.00ml, not more than 1000 ~ 1500ml within 24 hours. The amount of the baby is 5 ml/kg, and the amount of the child is 10 ml/kg.
2. Shock cases: the dosage can be larger, the speed can be faster, the infusion rate is 20-40 ml/min, and the maximum dose can be 20 ml/kg on the first day, and the dehydration must be corrected before use.
3. Prevention of postoperative thrombosis: 500ml during or after surgery, usually 500ml / day on the first and second day after surgery, intravenous infusion at a rate of 2 to 4 hours, high-risk patients, the course of treatment can be used up to 10 days.
4. Vascular embolism disease: should be slowly intravenous infusion, generally 250 ~ 500ml each time, daily or every other day, 7 to 10 times for 1 treatment
Dextran hypromellose eye drops: According to the condition, eye drops, 1-2 drops each time.

[Storage]
Low molecular weight dextran amino acid injection: shading, stored below 25 ° C
Compound dextran 40 injection: shading, confined preservation
Dextran 40 Glucose Injection: Store below 25 ° C
Dextran hypromellose eye drops: shading, sealed preservation

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

Parkinson , Acromegaly

Lennox-Gastaut syndrome , epilepsy

Thalassemia , Thalassemia

Thalassemia , Thalassemia

scleroderma , Paroxysmal nocturnal hemoglobinuria