name
Attention: The internal data of table “708” is corrupted!
Mekasmin
【Product name】Increlex
[English common name]Mecasermin
[Chinese common name]Mekasmin
[English name]Mecasermin [INN:BAN]
[Chinese other name]Humanized mekamin
[Indications] Mecamaster is mainly used for long-term treatment of severe primaryIGF-1Lack of children, or loss of growth hormone (GH) gene and insufficient growth of GH neutralizing antibodies in the body. Mecamaster cannot be used to treat secondary IGF-1 deficiency (eg, IGF-1 deficiency due to GH deficiency, malnutrition, hypothyroidism, or long-term use of hormone anti-inflammatory therapy).
[Usage and Dosage] Mecamaster is a clarified sterile injection with a specification of 4ml: 40mg. Mecamaster should be administered in a personalized manner, with an initial dose of 0.04 to 0.08 mg/kg (40 to 80 μg/kg), twice a day, subcutaneously. If the patient is well tolerated after 1 week of administration, the dosage of mecamylamine can be increased by 0.04 mg/kg per dose until the maximum dose is 0.12 mg/kg (2 times a day). The investigators have not evaluated clinical manifestations of doses above 0.12 mg/kg in children with primary IGF-1 deficiency, and because of the possible hypoglycaemic response, it is recommended that the dose of mecamylamine not exceed 0.12 mg/kg. .
If the patient still has a hypoglycaemic response with the recommended dose of mecamylamine and sufficient food intake, the dose of mecamylamine should be moderately reduced. Mecamylamine should be administered within a short period of time (approximately 20 minutes) before or after a meal or meal. If the patient is unable to eat before and after administration, the administration should be cancelled. Moreover, at the time of the next administration, the patient cannot arbitrarily increase the dose due to the previous administration. When the drug is administered by mecamylamine, the different administration sites should be alternately replaced in turn, and should not be fixed at the same site.
[Storage] Mecamsamine should be stored in the dark at 2-8 °C and should not be frozen. When the vial is opened, the mecamylamine can be stored stably at 2-8 °C for 30 days.
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
product
Attention: The internal data of table “709” is corrupted!
product manual
Related products
-
Dwarf syndrome , Congenital hyperinsulinemia
insulin
【Product name】Insulin, Ryzodeg, Tresiba, Xultophy, NOVOLIN, AFREZZA
[English common name]Insulin
[Chinese common name]insulin
[English name]Insulin injection
[Chinese other name]Insulin injection
[indications]
Humanized special insulin injection:
1. For the treatment of type 1 diabetes in adults and children.
2. Also available forType 2 diabetesPatients supplemented with long-acting insulin to control their hyperglycemia.
Protamine zinc recombinant human insulin mixed injection: This product is mainly used to treat type I or type II diabetes.
30/70 mixed recombinant human insulin injection: type I or type II diabetes.
Low-protamine recombinant human insulin injection: This product is mainly used to treat type I or type II diabetes.
50/50 mixed recombinant human insulin injection: type 1 or type 2 diabetes.
Conventional recombinant human insulin injection: This product is suitable for the treatment of diabetic patients who need insulin to maintain blood sugar levels. It is also suitable for early treatment of early diabetic patients and for the treatment of diabetic patients during pregnancy.
Recombinant insulin glargine injection: This product is suitable for diabetes.
Adenine triphosphate coenzyme for injection: for the improvement of symptoms such as hepatitis, nephritis, cirrhosis, heart failure and the like.【Dosage】
Humanized special insulin injection: subcutaneous injection, 1 or 2 times a day, the dose depends on the blood glucose concentration. Oral hypoglycemic drugs can not control type 2 diabetes, if the patient has not used insulin therapy, the initial dose of this product is 0.1 ~ 0.2U / kg, once a day, or 10U each time, 1 or 2 times a day. Dosage conversion is available for patients with type 1 and type 2 diabetes who are receiving general insulin therapy when switching to this product.
Protamine zinc recombinant human insulin mixed injection: The clinician determines the therapeutic dose of insulin administered to the patient according to the actual demand of the patient. It should be administered by subcutaneous injection, although it is not recommended but can also be administered intramuscularly. It can not be administered by intravenous injection. The upper arm, thigh, buttocks or abdomen should be selected for subcutaneous injection. At the same time, attention should be paid to the rotation of the injection site. The number of injections per month for the same site should not exceed one. Care should be taken during injections to ensure that blood vessels are not pierced. When the injection is completed, the injection site cannot be sputum. Patients should be aware of the correct method of administration by injection. a) The preparation of the dose should be inverted 10 times in the hand and 10 times in the 180° before use to ensure that the insulin preparation shows a uniform turbid or milky state at the time of injection.
30/70 mixed recombinant human insulin injection:
Instructions:
1. Check if the refill is consistent with the doctor's recommended specifications before use.
2. Method of preparing insulin: According to the method of using Dongbao pen, correctly insert the refill into the refill holder, and then install the Dongbao needle. Slowly invert the Dongbao pen 8 to 10 times to make the liquid in the refill mix evenly. Turn the dose adjustment knob to adjust to the desired dose. After removing the needle cap and draining the air bubbles, you can inject it. Be careful not to touch the needle with anything during use to prevent contamination.
3. Selection of injection site: The injection site should choose the looser part of the skin, such as the upper arm, thigh, buttocks and abdomen. The injection site should alternate in turn. The same site can not be injected twice in two weeks. Each injection site should be The last injection site was about 1 cm apart.
Low-protamine recombinant human insulin injection:
Instructions:
1. This product is a white or off-white suspension. It is injected subcutaneously about 1 hour before breakfast and dinner. The specific time is determined by the doctor according to the patient's condition.
2. Method of preparing insulin: first wash your hands, gently shake or turn the medicine bottle to mix the liquid evenly, and carefully check the appearance of the insulin taken, remove the plastic protective cap, expose the rubber stopper, use 75% alcohol Wipe the stopper, if using one type of insulin, inhale the syringe into the air equivalent to the insulin dose, insert the needle into the stopper, inject the air into the tube, invert the syringe and the vial, hold it with one hand and gently shake it. Make sure the top of the needle is below the liquid level and then use the other hand to push the pusher back to extract the correct amount. Check the tube for bubbles before withdrawing the needle.
50/50 mixed recombinant human insulin injection:
Instructions:
1. Check if the refill is consistent with the doctor's recommended specifications before use.
2. Method of preparing insulin: According to the method of using Dongbao pen, after installing the refill correctly into the refill holder, install the Dongbao needle. Slowly invert the Dongbao pen 8-10 times to make the liquid in the refill mix evenly. Turn the dose adjustment knob to adjust to the desired dose. After removing the needle cap and inserting the air bubbles, you can inject it. Be careful not to touch the needle with anything during use to prevent contamination.
3. Selection of injection site: The injection site should choose the looser part of the skin, such as the arms, thighs, buttocks and abdomen, etc. The injection site should alternate in turn. The same part can not be injected continuously for two weeks within two weeks. The last injection site was about 1 cm apart.
Conventional recombinant human insulin injection:
1. This product is a white suspension. It is injected subcutaneously about 1 hour before breakfast and dinner. The specific time is determined by the doctor according to the condition.
2. Method of using insulin: Be careful not to touch the needle number with any object during use to prevent contamination. If it is to be mixed with recombinant human insulin injection, it should be carried out under the guidance of a doctor. Before extracting recombinant human insulin, the vial should be placed in the palm of the hand and gently rolled until the insulin is in a uniform suspension. The same amount of low-protamine recombinant human insulin is extracted with a syringe, and the air is injected into the reconstitution. Inside the human insulin bottle, then pull the needle out. The same amount of air as the conventional recombinant human insulin is injected with a syringe, and the air is injected into a conventional recombinant human insulin bottle, and then the vial and the syringe are inverted.
Recombinant insulin glargine injection:
1. Usage.
2. Insulin glargine has a long-acting effect, and can be injected subcutaneously once a day.
3. Insulin glargine should be administered subcutaneously and return to room temperature before injection. Please follow the steps below when injecting,
(1) Observe the appearance of the liquid in the bottle. Normally it should be a colorless clear solution. Do not continue to use if the appearance is cloudy, slight color changes, or visible particles.
(2) Remove the plastic protective cap before using the new drug, but do not remove the stopper. Wipe the top of the bottle and the stopper with a 75% alcohol cotton ball before each use.
(3) Draw the same amount of air as you need insulin glargine, insert the needle into the stopper and inject the air into the needle.
(4) Hold the vial upside down with one hand.
Injectable adenosine triphosphate coenzyme insulin: intravenous injection. Dilute with 25% glucose injection and slowly inject. Intravenous drip. After instillation with 500 ml of 5% glucose injection, the instillation was carried out. Intramuscular injection. After injecting 2 ml of sodium chloride injection, it was injected. One day, 2-6 weeks for a course of treatment.[Storage]
Humanized special insulin injection: 2 ~ 8 ° C preservation, to avoid freezing. The opened injection can be stored for 42 days at 30 ° C or less.
Protamine zinc recombinant human insulin mixed injection: sealed.
30/70 mixed recombinant human insulin injection: This product should be stored in the refrigerator at 2 ~ 8 °C before use, do not freeze or close to the ice tray, frozen insulin can not be used, the refill stored in the insulin injection pen Do not store in the refrigerator, the patient can carry it for one month without being exposed to direct sunlight or hot drama.
Low-protamine recombinant human insulin injection: sealed.
50/50 mixed recombinant human insulin injection: This product should be stored in the refrigerator at 2-8 °C before use. The refill stored in the insulin injection pen should not be stored in the refrigerator. The patient can avoid direct sunlight or cold. Carry it with you for a month under the hot conditions.
Conventional recombinant human insulin injection: confined preservation.
Recombinant insulin glargine injection: sealed and stored.
Injectable adenosine triphosphate coenzyme insulin: sealed, kept in a cool place (not more than 20 ° C).[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
-
Dwarf syndrome
Insulin-like growth factor
【Product name】Increlex
[English common name]IGF-1
[Chinese common name]Insulin-like growth factor
[English name]Somatomedin C
[Chinese other name]Growth promoting factor
[indications]
Osteoporosis
IGF-1 can promote the matrix synthesis of bone, inhibit the catabolism of bones, prevent the loss of calcium in bones, and maintain the normal structure and function of bones. Therefore, the effect is obvious in the prevention and treatment of osteoporosis.
diabetes
The hypoglycemic effect of IGF-1 is similar to that of insulin, especially for insulin-independent diabetes.Type II diabetesThere is a direct effect. Experiments have shown that in patients with type 2 diabetes, the glucose concentration in the blood decreased on the second day of IGF-1 treatment, and it was normal on the fourth to fifth days.
Cardiovascular diseases
The vasospasm of IGF-1 also makes it a place in the treatment of cardiovascular diseases, especially in the treatment of heart failure caused by myocardial infarction. IGF-1 can effectively prevent myocardial ischemia-reperfusion injury.【Dosage】Promote growth: IGF-1 is very important in the human body.MitosisPromoter.
[Storage]Increlex vial®[2o to 8°C (35o to 46oF) is stable when refrigerated. Avoid freezing Increlex vials®. Avoid direct light.
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
简体中文