Tacros

【Product name】Putti, Envarsus, MODIGRAF, PROGRAF, Tacrolimus, ASTAGRAF

[English common name]Tacrolimus

[Chinese common name]Tacros

[English name]Big ring piperon, Taikelima

[Chinese other name]Macrocyclic melam, texley horse

[indications]
Tacrolimus Sustained Release Capsule: Prevents graft rejection after liver or kidney transplantation.
Tacrolimus injection:
1. Prevention of graft rejection after liver or kidney transplantation.
2. Treatment of graft rejection after liver or kidney transplantation using other immunosuppressive drugs.
Tacrolimus ointment: This product is suitable for patients with moderate to severe atopic dermatitis who are not suitable for traditional treatment due to potential risks, or who have not responded to traditional therapies or cannot tolerate traditional therapy, as short-term or intermittent long-term treatment. .
Tacrolimus capsule: Prevents graft rejection after liver or kidney transplantation.

【Dosage】
Tacrolimus Sustained Release Capsules:
1. Recommended starting dose for oral administration of Prograf in adults after surgery:
(1) For patients with liver transplantation, the initial oral dose should be 0.1-0.2 mg/kg per day by weight, taken orally twice, and started 6 hours after surgery.
(2) For kidney transplant patients, the initial oral dose should be 0.15-0.3 mg/kg per day by weight, divided into two orally, and the drug should be started within 24 hours after surgery.
2. Rejection that is ineffective against traditional immunosuppressive therapy:
(1) For patients with rejection and traditional immunosuppressive therapy, patients should start treatment with Prograf. The recommended starting dose is the same as the level of first immunosuppressive agent.
Tacrolimus injection: The following recommended doses for oral and intravenous administration are only general indicators. The actual dose of the drug should be adjusted according to the needs of individual patients. The recommended dose is only the initial dose, so the treatment should be The clinical judgment was supplemented with monitoring of the concentration of tacrolimus in the blood to adjust the dose.
1. Oral administration: The daily dose is administered in two divided doses. It is best to take capsules on an empty stomach or at least 1 hour before eating or 2-3 hours after eating to achieve maximum absorption. Oral capsules are usually administered continuously to inhibit transplant rejection and have no limitations during treatment.
2. Intravenous administration:
(1) The concentrate for infusion must be diluted with 5% glucose or physiological saline in polyethylene or glass bottles.
Tacrolimus ointment:
1. Adult 0.03% and 0.1% tacrolimus ointment Apply a thin layer of this product on the affected area, gently rub it, and cover it completely, twice a day, until the atopic dermatitis symptoms and signs disappear one week. Encapsulation therapy may promote systemic absorption and its safety has not been evaluated. This product should not be used for external application of package dressings.
2. Children 0.03% tacrolimus ointment Apply a thin layer of this product on the affected area, gently rub it, and cover it completely, twice a day, until a week after the disappearance of atopic dermatitis symptoms and signs. Encapsulation therapy may promote systemic absorption and its safety has not been evaluated. This product should not be used for external application of package dressings.
Tacrolimus capsule:
1. Recommended starting dose for oral administration of Prograf in adults after surgery:
(1) For patients with liver transplantation, the initial oral dose should be 0.1-0.2 mg/kg per day by weight, taken orally twice, and started 6 hours after surgery.
(2) For kidney transplant patients, the initial oral dose should be 0.15-0.3 mg/kg per day by weight, divided into two orally, and the drug should be started within 24 hours after surgery.
2. Rejection that is ineffective against traditional immunosuppressive therapy:
(1) For patients with rejection and traditional immunosuppressive therapy, patients should start treatment with Prograf. The recommended starting dose is the same as the level of first immunosuppressive agent.
(2) The patient is converted from cyclosporine to prograf, and the first dose interval of Prograf is no more than 24 hours.

[Storage]
Tacrolimus Sustained Release Capsules: sealed, stored in a cool, dry place.
Tacrolimus injection: shading, sealed and preserved.
Tacros ointment: sealed.
Tacrolimus capsule: sealed, placed in a cool place.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.