Carglutamic acid
【Product name】Carbaglu
[English common name]Carbaglu
[Chinese common name]Carglutamic acid
[English name]Kar GLOO mik AS id, N-Carbamylglutamate
[Chinese other name]N-carbamoyl-L-glutamic acid, N-carbamoyl-L-glutamic acid
[Indications] carbaglu (carglumic acid) is a carbamyl phosphate synthetase 1 (CPS 1) activator expressed as: the adjuvant treatment of acute hyperammonemia due to the deficiency of liver enzyme N-acetyl synthase (NAGS) . Maintenance therapy is used to treat chronic hyperammonemia due to the deficiency of liver enzymes N-acetylglutamate synthase (NAGS).
【Dosage】
Carbaglu treatment should be initiated, with metabolic disorders by experienced physicians.
Adult dose and method of administration
The recommended initial dose range for acute hyperammonemia is 100 mg/kg/day to 250 mg/kg/day.
The recommended maintenance dose is titrated for the age, the target of normal blood ammonia levels.
Divide to be given immediately before meals or feeding, the total daily dose is 2 to 4 times.
Each split dose should be rounded to the nearest 100 mg.
Each 200 mg tablet should be dispensed in a minimum of 2.5 ml of water and taken immediately.
Carbaglu can be taken orally or through the nasogastric tube.
Carbaglu tablets should not be swallowed or shredded.
Pediatric dosage and administration method
The recommended initial dose range for acute hyperammonemia is 100 mg/kg/day to 250 mg/kg/day.
Recommended maintenance doses are titrated for the target age of normal plasma ammonia levels.
Divide to be given immediately before meals or feeding, the total daily dose is 2 to 4 times.
In 2.5 ml of water, obtain a solution of 80 mg / mL of each 200 mg tablet.
Oral administration can be carried out using an oral syringe or through a nasogastric tube.
Carbaglu tablets should not be swallowed or crushed.
Clinical studies in other foods and liquids are therefore not recommended.
[Storage] Store in the refrigerator (2 ° C – 8 ° C) After opening the tablet container for the first time: Do not refrigerate. Do not store above 30C. Keep container tightly closed to prevent moisture.
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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