Mirafarin

【Product name】Mepact

[English common name]Mifamurtide

[Chinese common name]Mirafarin injection

[English name]L-MTP-PE

[Chinese other name]

[Indications] Treatment of non-metastatic high-grade excision after complete resection of macroscopic surgery in children, adolescents, and young adults. The drug was evaluated in conjunction with more "post-chemotherapy. Safety and efficacy have been established at the age of between 2 and 30 years of age".

[Usage and Dosage] Treatment should be initiated and supervised by experienced specialists in the diagnosis and treatment of osteosarcoma. The recommended dose for all patients with mifamurtide and the '2 mg/m2 diarea body surface.
The agents must be adjuvanted with somministratocome as follows: at a distance of 12 weeks from each other at least 3 days per week, then transferred to treatment once a week for another 24 weeks for a total of 48 infusions for 36 weeks.
Pediatric patients: Safety and effectiveness have been established from two-year-old children. Use did not qualify with "medicinal use in the following children due to lack of safety and effectiveness didate 2 years.
Elderly patients: Osteosarcoma studies include patients 65 years of age and older. In a randomized phase III study, only patients were "up to 30 years old."
Therefore, there is not enough data to recommend middle-aged patients "more than 30 years of use of the product. The patient's kidney or liver function damage: the characteristics of the patient's kidney or liver function damage farmacocinetichedi mifamurtide has not been formally studied. It is recommended to be careful about conquesti patients because there is no Any information on the amount. Continuous monitoring of renal and liver function is recommended if the drug is used beyond the completion of chemotherapy until the treatment is completed.
Mododi Management: The product should be reconstituted, using a filter, and provided for further dilution filtration prior to administration. Reconstitute the suspension for infusion, filter, and 'opaque liposome suspension evenly, white to off-white, no visible particles and free foam and lipid lumps.
Once reconstituted, it is further diluted using a filter provided, and the drug is administered by intravenous infusion within one hour. The drug should not be administered as a bolus injection.

[Storage] Store in the refrigerator (2 degrees Celsius – 8 degrees Celsius). Do not freeze. Keep the vial of the outer box to protect the medicinaledalla light.

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