Recombinant human N-acetylgalactosamine-6-sulfate sulfatase

【Product name】Vimizim

[English common name]Elosulfase alfa

[Chinese common name]Recombinant human N-acetylgalactosamine-6-sulfatase

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[Indications] Vimizim (elosulfase alfa) is suitable forIVA type mucopolysaccharidosis (MPS IVA; Morquio A syndrome)patient.

[Usage and Dosage] The recommended dose is 2 mg / kg intravenously, the minimum range is 3.5 to 4.5 hours, based on the infusion volume, once a week. It is recommended to use antihistamines or no antipyretics for pre-treatment 30 to 60 minutes before the start of the infusion.

[Storage] Store Vimizim at a refrigerated temperature between 2 ° C and 8 ° C (36 ° F to 46 ° F). Do not freeze or shake. Protected from light. The diluted Vimizim should be used immediately. If not immediately available, the diluted Vimizim can be stored for up to 24 hours at 2 ° C to 8 ° C (36 ° F to 46 ° F) and then stored at 23 ° C to 27 ° C for up to 24 hours (73 °F to 81 °F during application).

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