Low-protamine recombinant human insulin injection Chinese description 4

Common name:

Low-protamine recombinant human insulin injection

product name:

Gan Shulin N

Drug classification:

Biological Products

Drug properties:

prescription

Related diseases:

diabetes,

Traits:

This product is a white or white-like sterile suspension liquid that can be evenly dispersed after shaking.

main ingredient:

The active ingredient of this product is: recombinant human insulin.

Indications:

This product is mainly used to treat type I orType II diabetes.

specification:

3 ml / 300 units / refill

Adverse reactions:

The literature reported occasional local redness,

Allergic reactions such as itching and local subcutaneous lipid hyperplasia. Systemic allergic reactions (systemic rash, shortness of breath, asthma, decreased blood pressure, rapid pulse, hyperhidrosis, and severe life-threatening cases) are rarely reported.

1. Lipid dystrophy, subcutaneous injection of insulin rarely causes lipid atrophy or lipid proliferation. If this happens, you must inform your doctor. Changing injection techniques may improve this.

2. insulinallergy,

(1) Local allergic reactions. Occasionally, the patient's injection site is red and swollen, which is called local allergy. It usually disappears within a few days or weeks. In some cases, it may be caused by other causes and has nothing to do with insulin injection. If the skin disinfectant is irritated, the injection technique is not good, etc., if a local reaction occurs, immediately inform the doctor.

Dosage:

Instructions:

1. This product is a white or off-white suspension. It is injected subcutaneously about 1 hour before breakfast and dinner. The specific time is determined by the doctor according to the patient's condition.

2. Method of preparing insulin: first wash your hands, gently shake or turn the medicine bottle to mix the liquid evenly, and carefully check the appearance of the insulin taken, remove the plastic protective cap, expose the rubber stopper, use 75% alcohol Wipe the stopper, if using one type of insulin, inhale the syringe into the air equivalent to the insulin dose, insert the needle into the stopper, inject the air into the tube, invert the syringe and the vial, hold it with one hand and gently shake it. Make sure the top of the injection needle is below the liquid level and then use the other hand to push the pusher backwards to extract the correct amount. Before withdrawing the needle, check the needle tube for bubbles. If there are air bubbles, the needle can be used.

Taboo:

Those with a history of insulin allergy are banned.

Precautions:

1. Diabetic patients should check their blood sugar or urine sugar regularly. If the blood glucose test continues to be higher or lower than normal or the urine sugar continues to be positive, indicating that diabetes is not properly controlled, the doctor must be informed, often enough insulin, as well as syringes and needles. Diabetes patient identification documents are often worn to ensure proper treatment when complications occur from home.

2. Any changes in insulin application must be taken care of and should be performed under the guidance of a doctor. Every time you use insulin, you should carefully check the purity, potency, registered trademark, type, species (bovine, pig, human), production method (recombinant human insulin, animal purified insulin) recommended by the doctor, any Changes in the above items will result in a change in dosage.

3. Patients who used animal insulin in the past were switching.

Pregnant women and lactating women:

Pregnancy makes diabetes more difficult to control, so pregnant women who are planning to become pregnant and pregnant or breastfeeding must consult a doctor.

Pediatric medication:

Children should pay attention to exercise volume and diet when using this medicine in order to better control blood sugar. When using, the injection should be performed by the parent or doctor at the dose adjusted by the doctor.

Elderly medication:

During insulin therapy, hypoglycemia can occur if too much insulin is used. Mild to moderate symptoms of hypoglycemia may occur suddenly, often with the following manifestations: Sweat, drowsiness, dizziness, insomnia, heart palpitations, anxiety, trembling, blurred vision, hungry pronunciation, vagueness, feelings, low mood, hands, feet, lips, tingling, irritability, dizziness, abnormal energy Inconsistent behavior, unstable headache, personality changes, severe hypoglycemia, the symptoms are as follows: epilepsy Loss of consciousness is important in getting timely treatment when hypoglycemia occurs. In some cases, early hypoglycemia symptoms are not readily detectable. For example, patients with chronic diabetes, diabetic patients with neuropathy, and diabetic patients with beta blockers.

medicine interactions:

Oral contraceptives, adrenocortical hormones, and thyroid hormone replacement therapy can cause an increase in blood sugar, and the dose of insulin should be increased when applied. Oral hypoglycemic agents, salicylic acid preparations, sulfonamides, and certain antidepressants can cause a drop in blood sugar. At the same time, the application should reduce the dose of insulin. Avoid drinking alcoholic beverages.

Pharmacology and Toxicology:

This product is human insulin produced by recombinant DNA technology and has the same structure and function as natural insulin. It can regulate glucose metabolism, promote the uptake and utilization of glucose by liver, bone and adipose tissue, promote the conversion of glucose into glycogen and store it in muscle and liver, and inhibit gluconeogenesis, thereby lowering blood sugar.

Pharmacokinetics:

The subcutaneous injection of this product has a large difference in the onset and duration of the drug due to individual differences. Generally, the onset of action is slow after the injection, reaching a peak in 6 to 9 hours, lasting about 24 hours.

Storage:

seal

Validity period:

2 years