Sodium riboflavin sodium for injection Chinese description 5

Common name:

For injectionRiboflavinSodium phosphate

Drug classification:

chemical

Drug properties:

prescription

Related diseases:

Oral keratitis, conjunctivitis, scrotum, lip wind

Traits:

This product is a yellow or orange-yellow loose mass or powder.

main ingredient:

Riboflavin sodium phosphate.

Indications:

Riboflavin supplement. For the treatment of diseases such as keratitis, cheilitis, glossitis, conjunctivitis and scrotal inflammation caused by riboflavin deficiency.

specification:

5mg: 10mg / bottle

Adverse reactions:

1. When the kidney function is normal, the drug produces almost no toxicity.

2. Occasionally allergic reactions.

Dosage:

Subcutaneous, intramuscular or intravenous. 5 to 30 mg once a day, once a day.

Taboo:

Disabled for those who are allergic to this medicine.

Precautions:

Urine is yellow (or yellowish green) after a large amount of use of this drug, which can also cause symptoms similar to hyperthyroidism.

Pregnant women and lactating women:

The effect of this drug on pregnancy is not clear. This medicine can be secreted into milk, but breastfeeding is safe.

Pediatric medication:

still uncertain.

Elderly medication:

still uncertain.

medicine interactions:

Metoclopramide can reduce the absorption of the drug. Therefore, it is not suitable to use.

Pharmacology and Toxicology:

This product is a vitamin drug. Riboflavin (vitamin B2) is an important nutrient in the human body and plays a key role in energy metabolism. The drug is a flavin mononucleotide (FMN) and a flavin adenine dinucleotide (FAD) prodrug, while FMN and FAD are important cofactors for the flavozyme family. Flavinase catalyzes many biochemical reactions, most typically redox reactions, which are key factors in cellular respiration. FAD and FMN deliver hydrogen in the mitochondrial rotating chain, producing cellular energy during this process. In the absence of it, it can affect the body's biological oxidation, causing metabolic disorders, and its lesions are often manifested as inflammation of the mouth, eyes, and external genital area.

Pharmacokinetics:

There is no pharmacokinetic data for the administration of the drug. According to the literature, after oral administration of riboflavin, it is mainly absorbed in the proximal small intestine, food can promote the absorption of the product, and bile salts accelerate the absorption of the product. In the dose range of 2 to 25 mg, the bioavailability is 50 to 60%, and the maximum absorption per oral administration is 27 mg, and the excess portion is excreted from the feces. Flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) absorb less. The drug enters the blood circulation through the portal vein and reaches the tissue. Most of the serum riboflavin is transported by albumin or immunoglobulin and diffuses into the cell by a concentration gradient. In cells, riboflavin is converted to FMN by flavin kinase, which in turn is converted to FAD by FAD synthase.

Storage:

Protect from light and keep it sealed.

Validity period:

24 months