Lamotrigine
[Product Name]Lamictal
[English common name] Lamotrigine
[Chinese common name] Lamotrigine
[Other names in English] 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
[Chinese other name] Lamicot
[Indications] Epilepsy Bipolar disorder.
[Usage and Dosage] Oral, chewable or swallowed directly, or dissolved in a small amount of water. The initial dose of monotherapy for patients over 12 years old is 25mg once daily for 2 weeks; then 50mg once a day for two weeks. The dose is increased every 1-2 weeks, the maximum increase is 50-100 mg until the best effect is achieved, and the maintenance dose usually achieving the best effect is 100-200 mg/day, once or twice daily.
[Storage] Sealed.
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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Lennox-Gastaut syndrome , Familial spastic paraplegia
Clonazepam
【Product name】Rivotril
[English common name]Clonazepam
[Chinese common name]Clonazepam
[English name]Clonazepam methanol solution
[Chinese other name]Clonazepam
[indications]
Clonazepam injection: mainly used to control various typesepilepsyEspecially suitable for the absence of seizures,Infantile spasm,MyoclonicInsufficiency of exercise andLennox-Gastaut syndrome.
Clonazepam tablets: This product is mainly used to control various types of epilepsy, especially for absence seizures, infantile spasms, myoclonic, motor insufficiency and Lennox-Gastaut syndrome.【Dosage】
Clonazepam injection: The dosage should be individualized according to the specific conditions of the patient, and the intramuscular injection should be avoided as much as possible. The epileptic state can be controlled by intravenous injection. The adult dose is 1-4mg, and the injection is completed slowly in about 30 seconds. If the continuous state is still uncontrolled, the original dose can be repeated 1 or 2 times every 20 minutes. The maximum amount for adults is no more than 20 mg per day.
Clonazepam tablets:
1. The amount commonly used in adults: start with 0.5mg each time, 3 times a day, increase 0.5-1mg every 3 days, until the seizure is controlled or adverse reactions occur: the dosage should be individualized, the maximum amount of adults should not exceed 20mg per day. .
2. Commonly used in children: children aged 10 years old or younger than 30kg start to take 0.01~0.03mg/kg per day, take 2~3 times, then increase 0.25~0.5mg every 3 days, to reach 0.1% by weight per day. ~0.2mg/kg or an adverse reaction has occurred.
3. The course of clonazepam should not exceed 3 to 6 months.[Storage]
Clonazepam injection: shading, confined preservation.
Clonazepam tablets: sealed and preserved.[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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Lennox-Gastaut syndrome , Infant severe myoclonic epilepsy (Dravet syndrome)
Topiramate
【Product name】TOPINA
[English common name]Topiramate
[Chinese common name]Topiramate
[English name]Topmatt
[Chinese other name]Topemat
[Indications] This product is used for single-drug treatment of patients with newly diagnosed epilepsy or once combined with medication is now converted to monotherapyepilepsypatient. This product is used for the treatment of partial seizures in adults and children aged 2 to 16 years.
[Usage and Dosage] It is recommended to start treatment from low doses in adults and children, and then gradually increase the dose to adjust to the effective dose. Do not smash the tablets. This product is effective in treating partial seizures in adults and children. In the control treatment trials, it has been confirmed that the plasma concentration of topiramate has no correlation with clinical efficacy. There is no evidence that topiramate is tolerated in humans, and dose-ranging studies in patients with partial seizures in adults have shown that doses greater than 400 mg/day (600, 800, and 1000 mg/day) do not increase efficacy. When using this product, it is not necessary to monitor the plasma topiramate concentration for optimal efficacy. When this product is added with phenytoin, only a very small number of cases need to adjust the dosage of phenytoin to achieve the best clinical efficacy.
[Storage] Sealed.
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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Lennox-Gastaut syndrome
Ferric ester
【Product name】Felbatol
[English common name]Felbamate
[Chinese common name]Ferric ester
[English name]W 554, Felbamatum [Latin]; Felbatol
[Chinese other name]Non-urethane, non-Bammat
[indications]
1. Single or adjuvant therapy for or without systemic seizuresepilepsyPartial seizures.
2. Also available forLennox-Gastaut syndromeAuxiliary treatment.【Dosage】Conventional adult dose
The initial dose for oral administration is 1.2g per day, taken in 3-4 times, and can be increased by 0.6-1.2g every 1-2 weeks. The usual dose is 2.4-3.6g per day.
Child's regular dose
Oral administration of Lennox-Gastaut syndrome (supplemented with other antiepileptic drugs): children aged 2-14 years, 15mg/kg a day, 3-4 times orally, 15mg/kg every other week, the maximum daily dose is 45mg/kg. Children over the age of 14 use the same amount as adults.
Foreign usage and usage reference
Oral administration of adult episodes of partial seizures:
(1) The drug is treated with a single dose of 1.2 g per day, taken in 3-4 times. After the increase of 0.6g every 2 weeks, it can be increased to 2.4g a day, if necessary, up to 3.6g a day, in divided doses.
(2) The conversion from the combination to the single use of the drug, the initial dose of the drug is 1.2g a day, divided into 3-4 times, while other anti-epileptic drugs are reduced by 1/3; the second week of the drug increased to one day 2.4g, divided into 3-4 times, other anti-epileptic drugs reduced by 1/3; in the third week, the drug increased to 3.6g a day, divided into 3-4 times, other drugs continue to reduce to stop.
(3) The drug is used as an auxiliary drug for the treatment of partial seizures of epilepsy. The initial dose is 1.2g per day, divided into 3-4 times. At the same time, other antiepileptic drugs are reduced by 20%. After that, other drugs are gradually reduced to the minimum dose. The drug is dosed at a dose of 1.2g per week, and the maximum dose is up to 3.6g per day, taken in divided doses.
In patients with renal insufficiency, the dose of renal dysfunction should be adjusted according to renal function.
The dosage of elderly patients in the elderly is reduced.
Child's regular dose
Oral administration of Lennox-Gastaut syndrome: as an adjuvant, children aged 2-14 years, 15mg/kg a day, divided into 3-4 times, while other antiepileptic drugs are reduced by 20%; thereafter, a dose of 15mg/kg a week Increasing, up to the maximum dose of 45mg/kg a day, other drugs continue to reduce to the least adverse reactions. Children over the age of 14 use the same amount as adults.[Storage]20-25 ° C sealed storage
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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Lennox-Gastaut syndrome , Infant severe myoclonic epilepsy (Dravet syndrome)
Sodium valproate
【Product name】VALPROIC, Depacon
[English common name]Sodium Valproate
[Chinese common name]Sodium valproate
[English name] sodium, 2-propylpentanoate
[Chinese other name]Sodium 2-propylvalerate
[indications]
Sodium valproate tablets: mainly used for simple or complex absence seizures, myoclonic seizures, large seizures of single or combined medications, and sometimes have a certain effect on complex partial seizures.
Sodium valproate syrup: This product is used for systemic, partial or other types.epilepsy.【Dosage】
Sodium valproate tablets:
Adults commonly used: daily weight 15mg / kg or 0.6-1.2g (3-6 tablets) per day 2-3 times. Start with 5-10mg/kg, and increase it after one week until it can control the seizure. When the daily dosage exceeds 250mg, it should be taken in divided doses to reduce gastrointestinal irritation. The maximum daily dose is no more than 30mg/kg by weight, or 1.8-2.4g (9-12 pieces) per day. Commonly used in children: the same as adults, can also be 20-30mg/kg per day, divided into 2-3 times or 15mg/kg per day, increase by 5-10mg/kg every other week, to be effective or not Tolerance.
Sodium valproate syrup: Oral:
1 Adult commonly used amount: daily weight 15mg/kg or 600~1200mg daily, in divided doses. At the beginning, the body weight is 5-10 mg/kg, and it increases after one week until the seizure is controlled. When the daily dosage exceeds 250mg, it should be taken in divided doses daily to reduce gastrointestinal irritation. The maximum amount is generally not more than 30 mg/kg per day, or 1.8 to 2.4 g per day.
2 pediatric commonly used amount: the same as adults by weight. It has also been reported that at the beginning, the body weight is 15 mg/kg, and 5 to 10 mg/kg is added every other week as needed until it is effective or not tolerated.[Storage]
Sodium valproate tablets: sealed and stored in a dry place.
Sodium valproate syrup: shading, sealed, and kept in a cool dry place.[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.