Marizomib
【Product name】
[English common name]Marizomib
[Chinese common name]
[English name]NPI-0052, NPI0052, NPI-0052, UNII-703P9YDP7F
[Chinese other name]
[indications]
【Dosage】
[Storage]
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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Product information
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Multiple myeloma
Bortezomib
【Product name】VELCADE
[English common name]Bortezomib
[Chinese common name]Bortezomib
[English name]Dpba, Boronic acid, Bortizomib, Bortezomib for research
[Chinese other name]Botsomomi
[indications]
1. This product is used forMultiple myelomaThe patient's treatment, this patient has received at least two treatments before using this product, and the disease is still progressing in the latest treatment.
2. This product is used for recurrence or refractoryMantle cell lymphomaPatient's treatment, this patient has received at least one treatment before using this product. The safety and efficacy data for this indication comes from a single-arm phase II clinical study of a mantle cell lymphoma that has relapsed after previous treatment. There is still a lack of clinical research for the Chinese population.【Dosage】
1. Recommended dose for adult monotherapy This product is recommended for a single injection of 1.3 mg/m2, twice a week for 2 weeks (ie, on days 1, 4, 8 and 11). Days (ie from the 12th to the 21st day). 3 weeks is a course of treatment, and the two doses are at least 72 hours apart. For more than 8 courses of maintenance treatment, it can be administered according to standard protocols, or once a week, for 4 weeks of continuous maintenance (days 1, 8, 15 and 22), followed by a 12-day rest Period (22nd to 25th days).
2. Dose adjustment and restart treatment when it occurs. This grade should be discontinued when non-hematologic or any grade 4 hematologic toxicity (excluding neuropathy discussed below).[Storage] sealed and stored.
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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Hodgkin's disease , Multiple myeloma
Methyl benzamidine
【Product name】MATULANE
[English common name]Procarbazine
[Chinese common name]Methyl benzamidine
[English name]
[Chinese other name]
[indications]
1. Hodgkin's disease: can make 1/3 to 1/2 patients completely relieved, andNitrogen mustard,VincristineThe MOPP program consisting of prednisone is one of the basic programs for the treatment of Hodgkin's disease.
2. RightHodgkin's lymphomaMalignant histiocytosis (malignant histiocytosis), mycosis fungoides (sputum granuloma),Multiple myeloma,Melanoma,Brain tumorEtc. also has a certain effect.
3. In combination with radiotherapy, treatment shows a beneficial effect on radiation-resistant bronchial adenocarcinoma.【Dosage】
1. Oral: 150 to 300 mg per day, divided into 3 to 4 times, or 150 to 200 mg before bedtime, even for 2 weeks, repeated after 4 weeks, the total dose of one course depends on the blood, usually 7 ~ 9g . When the MOPP regimen is used to treat Hodgkin's disease, it is 100 mg/m2 per day for 14 days.
2. Intravenous infusion: 2 ~ 7mg / kg, gradually increased from the lower dose, a total of 7 ~ 10g a course of treatment.[Storage]Store at room temperature, sealed, and protected from light.
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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Multiple myeloma , scleroderma
Rituximab
【Product name】Rituxan
[English common name]Rituximab
[Chinese common name]Rituximab
[English name]
[Chinese other name]
[Indications] This product is suitable for: recurrent or drug-resistant follicular central lymphoma (international work classification B, C and D subtype B cell non-Hodgkin's lymphoma)Treatment. Previously untreated CD20-positive stage III-IV follicular non-Hodgkin's lymphoma, patients should be treated with standard CVP chemotherapy (Cyclophosphamide,VincristineAnd prednisone) 8 cycles of combined treatment. CD20-positive diffuse large B-cell non-Hodgkin's lymphoma (DLBCL) should be treated in combination with standard CHOP chemotherapy (cyclophosphamide, doxorubicin, vincristine, prednisone) for 8 cycles.
[Usage and Dosage] Usage and Usage Instructions Under the sterile conditions, the required dose of rituximab is taken and placed in a sterile non-pyrogenic infusion bag containing 0.9% saline or 5% dextrose solution. The concentration of rituximab was 1 mg/ml. Gently invert the injection bag to mix the solution and avoid foaming. As this product does not contain antimicrobial preservatives or bacteriostatic preparations, aseptic technique must be checked. The injection should be observed for particles or discoloration before intravenous use. Rituximab is diluted and administered intravenously through a dedicated infusion tube for the treatment of patients in ambulatory bed. The treatment of rituximab should be performed in a ward with complete resuscitation equipment and under the direct supervision of an experienced oncologist or hematologist. Monitor patients with respiratory symptoms or hypotension for at least 24 hours.
[Storage] Sealed.
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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Multiple myeloma
A-protease inhibitor
【Product name】Zemaira
[English common name]a lpha1-proteinase
[Chinese common name]A-protease inhibitor
[English name]
[Chinese other name]
[Indications] It is used to alleviate lung damage in patients with severe diseases.
[Usage and Dosage] The recommended dose is 60 mg per kg of body weight, once a week. The infusion should last for about 15 minutes.
[Storage] ZemairaTM remains stable for the life of the label when stored at temperatures up to 25 ° C (77 ° F). Avoid freezing, otherwise the container of the thinner may be damaged.
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.