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Related products

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  Acute lymphoblastic leukemia (Ph+ ALL) , Chronic myelogenous leukemia (CML)

  Punatinib

  【Product name】ICLUSIG

  [English common name]Ponatinib

  [Chinese common name]Punatinib

  [English name]

  [Chinese other name]

  [indications]Puntanib Iclusig is a kinase inhibitor suitable for the treatment of chronic or accelerated phase, or parental phase, for the treatment of resistance or inability to treat previous tyrosine kinase inhibitors.Chronic myelogenous leukemia (CML)Adult patients or Philadelphia chromosomes that are resistant or intolerant to previous tyrosine kinase inhibitor treatmentsAcute lymphoblastic leukemia (Ph+ALL). This indication is based on the response rate. No trials with Iclusig have been shown to improve disease-related symptoms or increase survival.

  【Dosage】45 mg with or without food orally once a day.

  [Storage]Store Iclusig tablets at 20° to 25°C (68° to 77°F); Allows an offset of 15° to 30°C (59° to 86°F).Stay away from children.

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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  Chronic myeloid leukemia , Gastrointestinal stromal tumor (GIST)

  Imatinib

  【Product name】Imatinib

  [English common name]GLEEVEC

  [Chinese common name]Imatinib

  [English name]Imatinib intermediates, imatinib

  [Chinese other name]Imatinib intermediate, imatinib

  [indications]
  Imatinib mesylate capsule: for treatmentChronic myeloid leukemia(CML) chronic phase, accelerated phase, or chronic phase after failure of alpha-interferon therapy; malignancy that cannot be surgically removed or metastasizedGastrointestinal stromal tumor (GIST)patient.
  Imatinib mesylate tablets: for the treatment of chronic chromosome patients with chronic myeloid leukemia (CML) in Philadelphia, in the blast phase, accelerated phase, or chronic phase after failure of alpha-interferon therapy.
  Adult patients for the treatment of malignant gastrointestinal stromal tumors (GIST) that cannot be removed and/or metastasized.

  【Dosage】
  Imatinib mesylate capsule: starting dose: for patients with blast crisis and accelerated phase of chronic myeloid leukemia, the recommended dose of imatinib mesylate is 600 mg/day; for chronic patients who have failed interferon therapy, and For patients with malignant gastrointestinal stromal tumors (GIST) who cannot be surgically removed or metastasized, the recommended dose is 400 mg/day, which is taken once a day. It is advisable to take the medicine at mealtime and drink a large glass of water. It should be taken continuously.
  If the blood picture permits, there is no serious adverse drug reaction, the dose can be considered to increase from 400mg / day to 600mg / day, or from 600mg / day to 800mg / day (400mg, divided into 2 times) in the following cases: disease progression, treatment A satisfactory hematologic response was not obtained after at least 3 months, and the hematologic response that had been obtained disappeared again.
  The dose must be adjusted in the following cases: if a serious non-hematologic adverse reaction (such as severe water retention) occurs during the treatment, the drug should be discontinued until the adverse reaction disappears, and then the dose is adjusted according to the severity of the adverse reaction.
  Dose adjustment in severe liver toxicity: If the bilirubin rises more than 3 times the upper limit of the normal range or the transaminase rises more than 5 times the upper limit of the normal range, the drug should be discontinued until the above indicators fall to 1.5 or 2.5 times the upper limit of the normal range. the following.
  Adjustment of dose during neutropenia or thrombocytopenia: accelerated or blast phase: if severe neutrophils and thrombocytopenia occur (neutrophils <0.5×109/L and/or platelets<10×109/L The recommended dose is reduced to 400 mg / day. If the blood cells continue to decrease for 2 weeks, further reduce the dose to 300 mg / day, if the blood cells continue to decrease for 4 weeks, it is advisable to stop the drug until neutrophils ≥ (greater than or equal to ) 1.0 × 109 / L and platelets ≥ (greater than or equal to) 20 × 109 / L. When used again, the dose is 300 mg / day.
  Patients with chronic phase after failure of α-interferon therapy: neutrophils <1.0×109/L and/or platelets <50×109/L should be discontinued, only in granulocyte ≥ (greater than or equal to) 1.5 When x109/L and platelet ≥ (greater than or equal to) 75×109/L, the dosage is 400 mg/day. If the neutrophils or platelets are reduced to the above values, the dosage will be restored. Reduced to 300 mg / day.
  Children and adolescents: There are no clinical data on the safety and efficacy of imatinib mesylate in patients under 18 years of age.
  Dosage in patients with liver failure: The plasma concentration of imatinib mesylate can be increased in patients with liver damage, so these patients should be cautious when using this drug. There is no liver damage in patients with liver damage. Nie's clinical data, no suggestion for dose adjustment.
  Renal failure and dose in elderly patients: creatinine clearance is known to decrease with age, and age has no significant effect on the pharmacokinetics of imatinib mesylate, as it has not been performed in patients with impaired renal function. Clinical trials, so it is not possible to propose a dose adjustment.
  Imatinib mesylate tablets: starting dose: The initial treatment should be performed by a physician with experience in treating chronic myelogenous leukemia or GIST.
  The product should be taken orally, and it is advisable to take the medicine while eating and drink a large glass of water. Usually adults once a day. Children and adolescents take it once or twice a day (morning and evening).
  Patients (children) who cannot swallow tablets can disperse the tablets in water or apple juice. It is recommended that pregnant and lactating women avoid contact with skin or eyes when inhaling capsules, or inhalation (see pregnant and lactating women), and wash hands immediately after touching open capsules.
  - therapeutic dose of CML patients
  adult
  The recommended dose for patients in the chronic phase is 400 mg/day, and for the blast phase and accelerated phase, it is 600 mg/day.
  As long as it is effective, it should be taken continuously.
  If the blood picture permits, there is no serious adverse drug reaction, the dose can be considered to increase from 400 mg / day to 600 mg / day, or from 600 mg / day to 800 mg / day (400 mg, orally, 2 times) Taking): The disease has not been able to obtain a satisfactory hematologic response after at least 3 months of treatment, and the hematological response has disappeared.
  Children and adolescents over 3 years old
  So far, children have limited experience in medication. According to the adult dose, the recommended daily dose is: chronic phase 260mg / m2 (maximum dose: 400mg), accelerated phase and blast phase 340mg / m2 (maximum dose: 600mg), the daily recommended dose for children, the calculated dose is generally Should be close to or around 100mg, the dose for children under 12 should generally be as close as possible or around 50mg. There is no experience in treating children under 3 years of age.
  - therapeutic dose of GIST patients
  For patients with malignant GIST who cannot be removed and/or metastasized, the recommended dose for this product is 400 mg/day.
  A satisfactory response was not obtained after treatment. If there were no adverse drug reactions, the dose could be considered to increase from 400 mg/day to 600 mg/day. Treatment time:
  For patients with GIST, the product should be treated continuously unless the condition progresses.

  [Storage]
  Imatinib mesylate capsule: should be kept below 30 °C.
  Imatinib mesylate tablets should be kept below 30 °C.

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
• 

  Moyamoya disease , scleroderma

  aspirin

  【Product name】Duoplavin, AUGMENTIN, Aspirin, COPLAVIX

  [English common name]Acetylsalicylic acid

  [Chinese common name]aspirin

  [English name]Acetyl salicylic acid

  [Chinese other name]Acetylsalicylic acid

  [indications]
  Aspirin dipyridamole sustained release capsule: This product is suitable for patients with transient ischemic attack or ischemic stroke caused by cerebral thrombosis, reducing the risk of occurrence or recurrence of stroke.
  Aspirin Zinc Capsule: It is used for fever caused by the common cold or influenza. It is also used to relieve mild to moderate pain such as headache, joint pain, migraine, toothache, muscle pain, neuralgia and dysmenorrhea.
  Aspirin chewable tablets: used to relieve mild or moderate pain, such as headaches and toothache. It is used to relieve fever and sore throat caused by cold.
  Aspirin Vitamin C effervescent tablets: used for fever caused by the common cold or influenza, but also used to relieve mild to moderate pain such as headache, joint pain, migraine, toothache, muscle pain, neuralgia, dysmenorrhea.
  Aspirin C enteric-coated tablets: used for fever caused by the common cold or influenza, but also used to relieve mild to moderate pain such as headache, joint pain, migraine, toothache, muscle pain, neuralgia, and dysmenorrhea.
  Aspirin enteric capsule: used for fever caused by the common cold or influenza, but also for mild to moderate pain such as headache, joint pain, migraine, toothache, muscle pain, neuralgia, dysmenorrhea.
  Aspirin sustained-release capsules: Aspirin sustained-release capsules are mainly used to inhibit platelet aggregation.
  Aspirin tablets: for the supplement of calcium and phosphorus in children, pregnant women, lactating women, can also be used to prevent and treat rickets.
  Aspirin enteric-coated tablets: used for fever caused by the common cold or influenza. It is also used to relieve mild to moderate pain such as headache, joint pain, migraine, toothache, muscle pain, neuralgia, and dysmenorrhea.

  【Dosage】
  Aspirin dipyridamole sustained-release capsules:
  1. Oral, 1 capsule per adult (aspirin 25mg and dipyridamole 200mg), twice daily, morning and evening. It can be taken with food or separated.
  2. This product should be swallowed whole and cannot be chewed.
  Aspirin zinc capsules: Oral, 1~2 capsules per adult. If the symptoms of fever or pain persist and do not relieve, repeat the medication once every 4 to 6 hours, and no more than 6 capsules within 24 hours.
  Aspirin chewable tablets:
  oral:
  1. One adult at a time, if the fever or pain is not relieved, the drug can be repeated once every 4-6 hours, and no more than 4 tablets in 24 hours.
  2. Children 1-8 years old 1/2 piece, 9-14 years old 2/3 pieces, 14 years old and above. Ingested after chewing.
  Aspirin Vitamin C Effervescent Tablets:
  oral:
  1. One adult at a time, if fever or pain is not relieved, repeat the drug once every 4-6 hours, no more than 4 tablets in 24 hours.
  2. Children 1/3 tablets once in 2-3 years, 1/2 tablets in 4-6 years old, 2/3 tablets in 6-10 years old, and 1 tablet in 10 years old and above. This product can be taken after being dissolved in an appropriate amount of warm water.
  Aspirin C enteric-coated tablets: oral. Adult, 2 tablets at a time, 3 times a day.
  Aspirin enteric-coated capsules: for small doses of antithrombotic application, 75-300 mg (1 to 4 capsules) per day, once a day.
  Aspirin sustained-release capsules: Oral: 50-150mg once a day, once a day, or as directed by your doctor.
  Aspirin tablets:
  1. Adults usually use oral
  (1) Antipyretic and analgesic: once 0.3~0.6g, 3 times a day, once every 4 hours if necessary.
  (2) Anti-inflammatory, anti-rheumatic: 3~6g a day, orally 4 times.
  (3) inhibition of platelet aggregation: low dose application. Ischemic stroke and transient ischemic attack, prevention of myocardial infarction, unstable angina pectoris, chronic stable angina pectoris, once 50 ~ 300mg, once a day; acute myocardial infarction, initial dose of 300mg, maintenance dose is 50~100mg daily; coronary artery bypass grafting (CABG), 300mg daily, can start 6 hours after surgery; percutaneous transluminal coronary angioplasty (PTCA).
  Aspirin enteric-coated tablets: Usage: Oral. Enteric-coated tablets should be served with an appropriate amount of water before meals.
  1. Reduce the risk of suspected patients with acute myocardial infarction: It is recommended to take 300mg for the first time, and take it after chewing to absorb it quickly. 100-200mg per day thereafter.
  2. Prevention of recurrence of myocardial infarction: 100-300 mg per day.
  3. Secondary prevention of stroke: 100-200 mg per day.
  4. Reduce the risk of transient ischemic attack (TIA) and its secondary stroke: 100-200 mg per day.
  5. Reduce the risk of angina in patients with stable and unstable angina: 100-300 mg per day.
  6. After arterial surgery or interventional surgery, such as percutaneous transluminal coronary angioplasty (PTCA), coronary artery bypass (CABG).

  [Storage]
  Aspirin Zinc Capsules: Store in a cool, dry place.
  Aspirin chewable tablets: sealed and kept in a dry place.
  Aspirin Vitamin C Effervescent Tablets: Sealed. Save below 25`C. Take it immediately after removal.
  Aspirin C enteric tablets: sealed.
  Aspirin enteric capsules: shading, sealed and preserved.
  Aspirin Extended Release Capsules: sealed and kept in a cool dry place.
  Aspirin tablets: sealed.
  Aspirin enteric-coated tablets: protected from light and sealed.

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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  Chronic myelogenous leukemia (CML) , Chronic myeloid leukemia

  Homoharringtonine

  【Product name】Homobarringtonie, Synribo

  [English common name]Homoharringtonine

  [Chinese common name]Homoharringtonine

  [English name]Ceflatonin

  [Chinese other name]High crude

  [Indications] for all types of acute non-lymphocytic leukemia,Myelodysplastic syndrome(MDS),Chronic myeloid leukemiaandPolycythemia veraThere is also a certain effect.

  【Dosage】
  1. Adult commonly used amount: intravenous drip, 1 ~ 4mg (1 ~ 4) per day, add 5% glucose injection 250 ~ 500ml, slowly drip for more than 3 hours, 4 to 6 days for a course of treatment, interval 1 Repeat the medication for ~2 weeks.
  2. Commonly used amount in children: intravenous drip, daily weight of 0.05 ~ 0.1mg / kg, 4 to 6 days for a course of treatment.

  [Storage] shading, sealed, and kept in a cool place.

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.