Rovastatin

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  Familial cold autoinflammatory syndrome , Mu-Wei's syndrome

  Lelosep

  【Product name】Arcalyst

  [English common name]Rilonacept

  [Chinese common name]Lilonase, Leloth

  [English name]

  [Chinese other name]Interleukin-1 receptor blocker

  [Indications] ARCALYST (rilonacept) is an interleukin-1 receptor blocker for the treatment of CryopyrinPeriodic syndrome(CAPS), including adults with familial cold autoinflammatory syndrome (FCAS) and Muckle-Wells syndrome (MWS) and children 12 years of age and older.

  [Usage and Dosage] Adults aged 18 years and older started treatment with a loading dose of 320 mg delivered to two 2 ml, subcutaneously 160 mg on the same day at two different locations. Continue to use a weekly injection of 160 mg as a single, 2 ml, subcutaneously administered dose. Don't give ARCALYST more often than once a week. Pediatric patients are 12 to 17 years old: the starting dose for treatment is 4.4 mg/kg, up to 320 mg, delivered with one or two subcutaneous injections, with a maximum single injection volume of 2 mL. Continue to administer a weekly injection of 2.2 mg/kg, up to 160 mg, as a single subcutaneous injection, up to 2 ml. If the initial dose given is two injections, they should be on the same day at two different locations. Don't give ARCALYST more often than once a week.

  [Storage]Freeze-dried ARCALYST products should be stored refrigerated in the original box at 2° to 8°C (36° to 46°F) to prevent light. Do not use outside the date stamped on the label. After reconstruction, ARCALYST may remain at room temperature and should be protected from light and should be used within three hours of reconstitution. ARCALYST contains no preservatives; therefore, the unused portion of ARCALYST should be discarded. Abandon the vial after taking the drug in a single dose.

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.