Alogliptin benzoate

【Product name】Nesina

[English common name]Alogliptin

[Chinese common name]Alogliptin benzoate tablets

[English name]Alogliptine, Alogliptina

[Chinese other name]Aglirel, Alorie Stop

[indications]This product is suitable for treatmentType 2 diabetes.
(1) monotherapy
This product is used as an adjunct to diet control and exercise to improve glycemic control in patients with type 2 diabetes.
(2) in combination with metformin hydrochloride
When metformin hydrochloride alone is not effective in controlling blood glucose, this product can be combined with metformin hydrochloride to improve glycemic control in patients with type 2 diabetes on a diet and exercise basis.
(3) Important use restrictions
Because the effectiveness of type 1 diabetes and diabetic ketoacidosis has not been determined, this product is not intended for patients with type 1 diabetes or diabetic ketoacidosis.

【Dosage】Recommended dose
1. Nishina's recommended dose is 25mg once daily.
2. Nishin can be taken at the same time or separately from the food.
3. Patients with impaired renal function
(1) Patients with mild renal impairment (creatinine clearance [CrCl] ≥ 60 mL / min) Nisin was not required to adjust the dose at that time.
(2) Patients with moderate renal impairment (creatinine clearance [CrCl] ≥ 30 to < 60 mL / min) The dose of Nishina was 12.5 mg once daily.
(3) Patients with severe renal impairment (creatinine clearance [CrCl] ≥ 15 to < 30 mL / min) or end-stage renal failure (ESRD) (CrCl < 15 mL / min or need hemodialysis) patients with Nishina dose For 6.25 mg once daily. Nixin can be used without considering dialysis time. Nishina medication studies have not been performed in patients undergoing peritoneal dialysis (see [Pharmacokinetics]).
Because of the need to adjust the Nishina dose according to renal function, it is recommended to evaluate renal function before starting treatment and review it regularly.

[Storage] Store at 25 ° C (77 ° F); Allow 15 ° to 30 ° C (59 ° to 86 ° F) offset [see USP controlled room temperature].

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

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