Bendamustine
【Product name】Treanda, Levact, Levact
[English common name]Bendamustine
[Chinese common name]Bendamustine
[English name]Treanda Powder Vial
[Chinese other name]
[indications]
1.Chronic lymphocyte leukemia(CLL). The efficacy of first-line therapy different from chlorambucil has not been established.
2. Inert B cells in the course of treatment with rituximab (rituximab) or rituximab regimen, or within 6 months of treatment, the condition is still progressingHodgkin's lymphoma(NHL) patients.
【Dosage】
Formulation process: The drug should be dissolved in 20 ml of sterile water for injection every 100 mg, and shaken thoroughly until it is completely dissolved into a clear, colorless or light yellow solution. The dissolution time is generally less than 5 minutes, and the concentration after dissolution is 5 mg/ml. Within 30 minutes after dissolution, an appropriate amount of aqueous solution of bendamustine was taken as needed, and transferred to 500 ml of sodium chloride injection (0.9%) or glucose sodium chloride injection (2.5%/0.45%) to ensure benzene. The final concentration of damolastine in the injection is between 0.2 and 0.6 mg/ml. The prepared injection can be stored at 2-8 ° C for 24 hours or at room temperature under natural light for 3 hours.
Bendamustine treatment of CLL takes 28 days as a treatment cycle and typically requires 6 treatment cycles. On the first and second days of each treatment cycle, the recommended dose is 100 mg/m2. The drug is administered by intravenous drip, and the time of each administration should not be less than 30 minutes.
Bendamustine treatment of NHL takes 21 days as a treatment cycle and typically requires 8 treatment cycles. On the first and second days of each treatment cycle, the recommended dose is 120 mg/m2. The time of each administration should not be less than 60 minutes.
[Storage] The storage temperature of the drug should not exceed 30 ° C, stored in the dark, and temporarily prepared before use.
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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Product information
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Chronic lymphocyte leukemia
Obiquitizumab
【Product name】Gazyva
[English common name]Obinutuzumab
[Chinese common name]Obiquitizumab
[English name]Ga101
[Chinese other name]
[indications]Chronic lymphocytic leukemia (CLL)
【Dosage】
Gazyvaro is a concentrate that can be made into an intravenous infusion solution and for more than a few hours. Gazyvaro treatment is given in six or eight cycles, each cycle lasting.
21 or 28 days.
For CLL, a 28 day period is used. A dose of 100 mg of GasyValo was administered on the first day of the first cycle.
Under the close supervision of an experienced doctor, he should monitor patient infusion related conditions.
reaction. If the patient does not take any medication, a second dose of 900 mg can be given on the same day.
reaction. If the reaction related to the infusion, the first dose of 100 mg, the second dose should be
Delay until the second day. A further dose of 1000 mg was then administered on days 8 and 15 of the first cycle. in order to
For the remaining 5 cycles, GayyVro 1000 mg is given only on day 1.
For FL, a dose of Gazyvaro 1000 mg was administered on days 1, 8, and 15 of the first 21 or 28 days of treatment.
cycle. For the remaining cycles, the dose is given only on day 1. For patients who respond to treatment,
May continue to receive Gazavar every two months for up to two years, as long as they benefit
From it. Patients can also take other medications to prevent infusion-related reactions and other side effects.[Storage]It can be stored at 2 to 8 ° C for up to 24 hours.
[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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