Tiravir

【Product name】INCIVEK

[English common name]Telaprevir

[Chinese common name]Tiravir

[English name]VX-950, Telaprevir, LY 570310

[Chinese other name]Trapivir

[Indications] INCIVEK is a kindHepatitis CViral (HCV) NS3/4A protease inhibitor is indicated for use in combination with peginterferon alfa and ribavirin for the treatment of genotype 1 chronic hepatitis C (CHC) in adult patients with compensated liver disease, Includes cirrhosis, untreated patients or patients who have previously been treated with interferon-based therapy, including those with previous zero response (Note: Hepatitis C virus load during treatment is minimal or no reduction), partial responders, and relapse By.
(1) INCIVEK must not be used as a monotherapy and must be used only in combination with peginterferon alfa and ribavirin.
(2) A high proportion of patients with previous zero response (especially those with cirrhosis) did not achieve sustained virological response (SVR) and there was a presence of telaprevir for treatment with INCIVEK with drug resistance.
(3) The efficacy of INCIVEK has not been determined in patients who have previously failed treatment with INCIVEK or other HCV NS3/4A protease inhibitor regimens.

【Dosage】
(1) 750 mg 3 times a day (interval 7-9 hours) and food (not low fat).
(2) For all patients, INCIVEK must be administered with both peginterferon alfa and ribavirin for a total of 12 weeks, followed by a reaction-guided regimen or 12 or 36 additional weeks of peginterferon alfa and ribba Welmin relies on viral reactions and previous reaction states.
(3) For specific dosage instructions for peginterferon alfa and ribavirin, refer to their corresponding prescription materials.

[Storage]Stored at 25oC (77oF); Allows an offset of 15-30oC (59-86oF).

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