Adenosine deaminase (ADA)

【Product name】Strimvelis, Adenosine Deaminase Antibody

[English common name]Adenosine Deaminase

[Chinese common name]Adenosine deaminase (ADA)

[English name]ADA

[Chinese other name]Adenine deaminase

[indications]Strimvelis is available for the treatment of severe combined immunodeficiency due to adenosine deaminase deficiency (ADA), a relevant stem cell donor who does not have a suitable human leukocyte antigen (HLA) match.

【Dosage】
Strimvelis must be performed by a professional transplant center, with ADA-SCID patient treatment and management experience and with a physician using autologous CD34 + ex vivo gene therapy products. Strimvelis should only be performed after consultation with patients and/or family members. Patients are expected to enter the post-treatment registry and will be followed for long-term follow-up.
CD34+ stem cells containing at least 1 million CD34+ cells per kilogram are required for use. This should be harvested from the patient at least 3 weeks prior to treatment with Strimvelis. If the product is manufactured after treatment with Strimvelis, failure occurs during transplantation or long-term bone marrow dysplasia, the stem cells are collected for use as salvage therapy.
Patients must be able to donate enough CD34+ cells to provide the minimum of 4 million purified CD34+ cells/kg required to make Strimvelis.
Strimvelis is for self-use only. Prior to infusion, the patient's identity must be confirmed to match the basic unique patient information on the Strimvelis infusion bag and/or container.

[Storage] shelf life of 6 hours, must be stored inAt 15-30 ° C.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

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Product information

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