Linaclotide

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  Carglutamic acid

  【Product name】Carbaglu

  [English common name]Carbaglu

  [Chinese common name]Carglutamic acid

  [English name]Kar GLOO mik AS id, N-Carbamylglutamate

  [Chinese other name]N-carbamoyl-L-glutamic acid, N-carbamoyl-L-glutamic acid

  [Indications] carbaglu (carglumic acid) is a carbamyl phosphate synthetase 1 (CPS 1) activator expressed as: the adjuvant treatment of acute hyperammonemia due to the deficiency of liver enzyme N-acetyl synthase (NAGS) . Maintenance therapy is used to treat chronic hyperammonemia due to the deficiency of liver enzymes N-acetylglutamate synthase (NAGS).

  【Dosage】
  Carbaglu treatment should be initiated, with metabolic disorders by experienced physicians.
  Adult dose and method of administration
  The recommended initial dose range for acute hyperammonemia is 100 mg/kg/day to 250 mg/kg/day.
  The recommended maintenance dose is titrated for the age, the target of normal blood ammonia levels.
  Divide to be given immediately before meals or feeding, the total daily dose is 2 to 4 times.
  Each split dose should be rounded to the nearest 100 mg.
  Each 200 mg tablet should be dispensed in a minimum of 2.5 ml of water and taken immediately.
  Carbaglu can be taken orally or through the nasogastric tube.
  Carbaglu tablets should not be swallowed or shredded.
  Pediatric dosage and administration method
  The recommended initial dose range for acute hyperammonemia is 100 mg/kg/day to 250 mg/kg/day.
  Recommended maintenance doses are titrated for the target age of normal plasma ammonia levels.
  Divide to be given immediately before meals or feeding, the total daily dose is 2 to 4 times.
  In 2.5 ml of water, obtain a solution of 80 mg / mL of each 200 mg tablet.
  Oral administration can be carried out using an oral syringe or through a nasogastric tube.
  Carbaglu tablets should not be swallowed or crushed.
  Clinical studies in other foods and liquids are therefore not recommended.

  [Storage] Store in the refrigerator (2 ° C – 8 ° C) After opening the tablet container for the first time: Do not refrigerate. Do not store above 30C. Keep container tightly closed to prevent moisture.

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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  other

  Lebowwood

  [product name] Bivol

  [English common name]Nebivolol

  [Chinese common name]Lebowwood

  [English name]NEBIVOLOL-D4, Nibivolol

  [Chinese other name]Nebirol

  [Indications] High blood pressure.

  [Usage and Dosage] The dose of BYSTOLIC must be personalized according to the needs of patients. For most patients, the recommended starting dose is 5 mg once daily, with or without food, monotherapy or in combination with other drugs. For patients who need to further lower their blood pressure, the dose can be increased to 40 mg at 2 week intervals. More frequent dosing regimens are unlikely to be beneficial.
  Renal insufficiency
  In patients with severe renal insufficiency (ClCr less than 30 mL / min), the recommended initial dose is 2.5 mg per day; if necessary, slowly titrate. The BYSTOLIC study has not been performed on patients undergoing dialysis [see Clinical Pharmacology.
  Liver damage
  In patients with moderate hepatic impairment, the recommended initial dose is 2.5 mg per day; if necessary, slowly titrate. BYSTOLIC has not been studied in patients with severe liver damage and is therefore not recommended for use in this population [see Clinical Pharmacology.

  [Storage] Storage temperature is 20 ° to 25 ° C (68 ° to 77 ° F).

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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  other

  Posaconazole

  【Product name】Noxafil

  [English common name]Posaconazole

  [Chinese common name]Posaconazole

  [English name]

  [Chinese other name]

  [indications]
  Oral suspension of posaconazole: NOXAFIL is a triazole antifungal drug expressed as: Invasive Aspergillus and Candida infection in patients 13 years of age and older, who are developing these infections due to severe immune function Low, such as hematopoietic stem cell transplant recipient graft versus host or those with hematologic malignancies and chemotherapy to prolong the prevention of neutropenia. Treatment of oropharyngeal candidiasis (OPC), including OPC refractory (ROPC), itraconazole and/or fluconazole.
  Posconazole tablets: prevention of invasive Aspergillus and Candida infections in patients 13 years of age and older; treatment of oropharyngeal candida infection; treatment of oropharyngeal candida infection resistant to fluconazole and itraconazole.

  【Dosage】
  Oral suspension of posaconazole: indication dose and treatment time
  Prevention of invasive fungal infections 200 mg (5 ml) three times a day. The duration of treatment is based on recovery from neutrophils or immunosuppression.
  Oral candidiasis (OPC) was loaded with a dose of 100 mg (2.5 ml) twice daily for the first day, then 100 mg (2.5 ml) once daily for 13 consecutive days.
  OPC refractory (RPC), with itraconazole and / or fluconazole 400 mg (10 ml) twice daily. The duration of treatment should be based on the severity of the patient's underlying disease and clinical response.
  Posaconazole tablets: The loading dose on the first day of treatment is 300 mg (ie 3 tablets of 100 mg sustained release tablets), twice a day; from the second day of treatment, the maintenance dose is 300 mg. (ie 3 tablets of 100mg sustained release tablets), once a day.

  [Storage] Store in a refrigerator at 2 ° C - 8 ° C.

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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  other

  Wattistatin

  【Product name】Brintellix

  [English common name]Vortioxetine

  [Chinese common name]Wattistatin

  [English name]

  [Chinese other name]

  [indications]The indication for BRINTELLIX is the treatment of depression (MDD).

  [Usage and Dosage] The recommended starting dose is 10 mg, once a day orally, regardless of the meal.
  The dose should then be increased to 20 mg/day as tolerated.
  Considering 5 mg/day, no one can tolerate a larger dose of the patient.
  BRINTELLIX can be discontinued suddenly. However, a recommended dose of 15 mg/day or 20 mg/day is completely stopped, if possible before being reduced to 10 mg/day for one week.
  The maximum recommended dose is known as CYP2D6 weak metabolism in 10 mg/day.

  [storage] willBrintellixStore at room temperature between 59 °F and 86 °F (15 °C to 30 °C).

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.