Posaconazole

【Product name】Noxafil

[English common name]Posaconazole

[Chinese common name]Posaconazole

[English name]

[Chinese other name]

[indications]
Oral suspension of posaconazole: NOXAFIL is a triazole antifungal drug expressed as: Invasive Aspergillus and Candida infection in patients 13 years of age and older, who are developing these infections due to severe immune function Low, such as hematopoietic stem cell transplant recipient graft versus host or those with hematologic malignancies and chemotherapy to prolong the prevention of neutropenia. Treatment of oropharyngeal candidiasis (OPC), including OPC refractory (ROPC), itraconazole and/or fluconazole.
Posconazole tablets: prevention of invasive Aspergillus and Candida infections in patients 13 years of age and older; treatment of oropharyngeal candida infection; treatment of oropharyngeal candida infection resistant to fluconazole and itraconazole.

【Dosage】
Oral suspension of posaconazole: indication dose and treatment time
Prevention of invasive fungal infections 200 mg (5 ml) three times a day. The duration of treatment is based on recovery from neutrophils or immunosuppression.
Oral candidiasis (OPC) was loaded with a dose of 100 mg (2.5 ml) twice daily for the first day, then 100 mg (2.5 ml) once daily for 13 consecutive days.
OPC refractory (RPC), with itraconazole and / or fluconazole 400 mg (10 ml) twice daily. The duration of treatment should be based on the severity of the patient's underlying disease and clinical response.
Posaconazole tablets: The loading dose on the first day of treatment is 300 mg (ie 3 tablets of 100 mg sustained release tablets), twice a day; from the second day of treatment, the maintenance dose is 300 mg. (ie 3 tablets of 100mg sustained release tablets), once a day.

[Storage] Store in a refrigerator at 2 ° C - 8 ° C.

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