Related drugs

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  • Growth hormone deficiency , Rare disease

    Recombinant human growth hormone

    【Product name】Ansumeng, NORDITROPIN, TEV-TROPIN, Genotropin

    [English common name]Recombinant human growth hormone

    [Chinese common name]Recombinant human growth hormone

    [English name]

    [Chinese other name]

    [Indications] This product has the same effect as human growth hormone, which can promote bone, visceral and systemic growth, promote protein synthesis, affect fat and mineral metabolism, and play a key role in human growth and development. About 80% of the subcutaneous injection was absorbed, and the peak blood concentration was reached after 5 hours, and t1/2 was about 4 hours. It is mainly used for growth disorders caused by insufficient secretion of endogenous pituitary growth hormone, dwarfism with short body, and short-term disease. In addition, it can be used to treat diseases such as burns, fractures, trauma, hemorrhagic ulcer, tissue necrosis, muscular dystrophy, and osteoporosis.

    [Usage and Dosage] The dosage of this product varies greatly. It is administered intramuscularly or subcutaneously. The dosage is 0.5-0.7 units/kg per week or 12 units/m2 per week, and it is administered 6-7 times.

    [Storage] Store at 2 ° C - 8 ° C. Valid for 1.5 years.

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

  • Acromegaly , Acromegaly

    Octreotide

    【Product name】Sandostatin, ANDOSTATIN

    [English common name]Octreotide

    [Chinese common name]Octreotide

    [English name]CCRIS 8708, L-Cysteinamide, UNII-75R0U2568I, SMS 201-995, L-Cysteinamide, 

    [Chinese other name]

    [indications]
    Octreotide acetate:
    1. Emergency treatment of esophageal-gastric varices bleeding caused by cirrhosis, combined with special treatment (such as endoscopic sclerotherapy).
    2. Alleviate the symptoms and signs associated with gastrointestinal pancreatic endocrine tumors. There is sufficient evidence that octreotide is effective against the following tumors: carcinoid tumors with carcinoid syndrome; VIP tumors, etc., octreotide is about 50% effective against the following tumors.
    (1) Gastrinoma/Zollinger-Ellison Syndrome (usually in combination with a selective H2 receptor antagonist, and an antacid may be added as appropriate).
    (2) Islet tumors (for the prevention of hypoglycemia before the operation of islet tumors, maintaining normal blood sugar).
    (3) Growth hormone releasing factor tumor. Treatment with octreotide acetate only reduces symptoms and signs, but does not cure.
    Octreotide acetate microspheres for injection: This product is used forAcromegalyFor the treatment of the following acromegaly patients: after subcutaneous injection of standard dose of Shan Ning, the condition is fully controlled; patients who are not suitable for surgery, radiotherapy or treatment, or in the potential reaction stage before radiotherapy is fully effective Patient. Patients with gastrointestinal pancreatic endocrine tumors associated with functional gastrointestinal pancreatic endocrine tumor-related symptoms have been adequately controlled by subcutaneous injection of Shan Ning. Carcinoid with the characteristics of carcinoid syndrome. Vasoactive intestinal peptide tumor. Glucagonoma. Gastrinoma / Zhuo-Ai syndrome. Insulinoma (for prevention and maintenance of preoperative hypoglycemia). Growth hormone releasing factor adenoma.
    Octreotide acetate for injection:
    1. Emergency treatment of esophageal-gastric varices bleeding caused by cirrhosis, combined with special treatment (such as endoscopic sclerotherapy).
    2. Prevention of postoperative complications of the pancreas.
    3. Alleviate the symptoms and signs associated with gastrointestinal endocrine tumors. There is evidence that this product is effective against the following tumors: carcinoid tumors with carcinoid syndrome; VIP tumors; glucagonoma. This product has an effective rate of about 50% for the following tumors (there are limited cases of treatment with this product to date): gastrinoma/Zollinger-Ellison syndrome. Islet tumor. Growth hormone releasing factor tumor.
    4. Patients with acromegaly who have failed surgery or radiation therapy or dopamine agonist therapy can control symptoms and reduce the concentration of growth hormone (GH) and auxin medium C.
    Octreotide acetate injection:
    1. Emergency treatment of esophageal-gastric varices bleeding caused by cirrhosis, combined with special treatment (such as endoscopic sclerotherapy).
    2. Alleviate the symptoms and signs associated with gastrointestinal pancreatic endocrine tumors. There is sufficient evidence that octreotide is effective against the following tumors: carcinoid tumors with carcinoid syndrome; VIP tumors, etc., octreotide is about 50% effective against the following tumors.
    (1) Gastrinoma/Zollinger-Ellison Syndrome (usually in combination with a selective H2 receptor antagonist, and an antacid may be added as appropriate).
    (2) Islet tumors (for the prevention of hypoglycemia before the operation of islet tumors, maintaining normal blood sugar).
    (3) Growth hormone releasing factor tumor. Treatment with octreotide acetate only reduces symptoms and signs, but does not cure.

    【Dosage】
    Octreotide acetate:
    1, esophageal - gastric varices bleeding continuous intravenous infusion of 0.025 mg / hour. It can be treated for up to 5 days and can be diluted with physiological saline or diluted with glucose solution.
    2, prevention of complications after pancreatic surgery 0.1 mg subcutaneous injection, 3 times a day, continuous treatment for 7 days, the first injection should be performed at least 1 hour before surgery.
    3, the initial dose of gastrointestinal pancreatic endocrine tumor is 0.05 mg subcutaneous injection, one to two times a day, and then gradually increase the dose to 0.2 mg according to tolerance and efficacy, three times a day.
    4. The initial dose of acromegaly is 0.05-0.1 mg subcutaneously, once every 8 hours, and then adjusted according to monthly assessment of circulating GH concentration, clinical response and tolerability.
    Octreotide Acetate Microspheres for Injection: This product can only be administered by deep injection into the buttocks muscle, but never by intravenous injection. If you penetrate the blood vessel, you need to change the injection site. Repeated injections should take turns to select different hip muscle injections on the left or right side. Acromegaly is recommended for patients who have complete control of the standard dose of subcutaneous injection of Shan Ning. The recommended initial dose of this product is 20 mg, administered once every 4 weeks for a total of 3 months. Treatment can begin 1 day after the last subcutaneous injection of Shan Ning. Thereafter the dose should be based on the concentration of serum GH and growth factor C (IGF-1) as well as clinical signs and symptoms. If clinical signs and symptoms and biochemical parameters (GH and IGF-1) are not fully controlled (GH > 2.5 ug/L) after 3 months, the dose should be increased to 30 mg once every 4 weeks.
    Octreotide acetate for injection:
    1. Esophagus - bleeding of gastric varices. Continuous intravenous infusion of 0.025 mg / hour. It can be treated for up to 5 days and can be diluted with physiological saline or diluted with glucose solution.
    2. Prevention of complications after pancreatic surgery. 0.1 mg subcutaneously, 3 times a day for 7 days, the first injection should be performed at least 1 hour before surgery.
    3. gastrointestinal pancreatic endocrine tumors. The initial dose is 0.05 mg subcutaneously, one to two times a day, and then gradually increased to 0.2 mg three times a day according to tolerance and efficacy.
    4. Acromegaly. The initial dose is 0.05-0.1 mg subcutaneously, once every 8 hours, and then adjusted according to monthly assessment of circulating GH concentration. Clinical response and tolerability.
    Octreotide acetate injection:
    1. Esophagus-gastric varices bleeding first 0.1mg intravenous bolus (5 minutes), then 0.6mg dissolved in 5% glucose 500ml, continuous intravenous infusion through the infusion pump at 50μg / hour, 12 hours once . Treat for up to 5 days.
    2. The initial amount of gastrointestinal pancreatic endocrine tumor is 0.05 mg subcutaneous injection, one to two times a day. The dose can be gradually increased to 0.2 mg three times a day based on tolerance and efficacy (clinical response, hormone concentration secreted by the tumor). In some cases, larger doses may be used. The maintenance amount should be based on individual differences. After the clinical symptoms and laboratory tests showed no improvement, the medication should not exceed one week.

    [Storage]
    Octreotide acetate: shading, sealed, stored in a cold place (2-10 ° C).
    Octreotide acetate microspheres for injection: sealed and stored in a cool place.
    Octreotide acetate for injection: sealed.
    Octreotide acetate injection: shading, sealed, stored in a cold place (2-10 ° C).

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

  • Parkinson , Acromegaly

    Cameron

    【Product name】Dostinex, CABASER

    [English common name]Cabergoline

    [Chinese common name]Cameron

    [English name]1-[(6-Allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)-propyl]-3-ethylurea

    [Chinese other name]6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl) ergoline-8-carboxamide

    [indications]
    For treatmentParkinson's Disease.
    2. forHyperprolactinemia.
    3. Try to useBreast cancer.

    [Usage and Dosage] Usage and dosage of different indications:
    Inhibition of physiological lactation: Adult: 1 mg, one-time administration on the first day after delivery. Liver damage: Adjust the dose.
    Inhibition of lactation: Adult: 250mcg / 12 hours for 2 days.
    Hyperprolactinemia-related diseases:
    Adult: initial dose: 500mcg / week, and then according to the reaction, add 500mcg per month, can be administered once a week or twice a day on different days; more than 1mg should be administered in divided doses.
    Conventional dose: 1 mg / week, up to: 4.5 mg / week. Take it at mealtime or after a meal.

    [Storage]The storage of commercial tablets should be controlled at room temperature (20 to 25 ° C, 68 to 77 ° F).

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

  • Acromegaly , Acromegaly

    Bromocriptine

    【Product name】Parlodel

    [English common name]Bromocriptine

    [Chinese common name]Bromocriptine

    [English name]

    [Chinese other name]

    [indications]
    1. Endocrine system diseases: prolactin-dependent menstrual cycle disorders and infertility (with high or normal prolactinemia), amenorrhea (with or without lactation), less menstruation, luteal function and drug-induced High prolactinosis (antipsychotics and treatments for hypertension).
    2. Non-prolactin-dependent infertility: polycystic ovary syndrome, combined with anti-estrogen (such as: chloralamine) for anovulation.
    3. Hyperprolactinoma: Conservative treatment of small pituitary adenomas, inhibiting adenoma growth or reducing the volume of adenoma before surgery, making excision easy; postoperative can be used to reduce the still higher prolactin levels.
    4.Acromegaly: Application alone or in combination with radiotherapy, surgery, etc. can reduce plasma levels of growth hormone.

    [Usage and Dosage] should be taken orally at mealtime
    1. Irregular menstrual cycle and infertility: According to the need, l/2 tablets (1.25mg with bromocriptine mesylate), 2-3 times a day, if necessary, the dose can be increased to 1 tablet (with A Bromocriptine sulfonate 2.5mg), 2 to 3 times a day. Treatment should be continued until the menstrual cycle returns to normal and/or re-ovulation. If necessary, several cycles of treatment can be continued to prevent recurrence.
    2. High prolactinosis: 1/2 tablet (1.25mg with bromocriptine mesylate), 2-3 times a day, gradually increased to 4-8 tablets per day (with methanesulfonic acid) Bromocriptine 10-20mg), the specific program should be based on clinical efficacy and side effects.
    3. Acromegaly: The recommended starting dose is 1-1.5 tablets a day.

    [Storage] The container is stored in a carton in the outer packaging (15-25 ° C). In the tropics, the container is placed in an outer carton and sealed to protect it from light and moisture.

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

  • Acromegaly , Acromegaly

    Lanreotide acetate

    【Product name】Somatuline

    [English common name]Lanreotide acetate

    [Chinese common name]Lanreotide acetate

    [English name]Somatuline

    [Chinese other name]Soma Dolin

    [Indications] Lanreitide acetate for injection is suitable forAcromegaly: abnormal growth hormone secretion after surgery and / or radiation therapy; treatment of clinical symptoms of carcinoid: after experimental injection.

    [Usage and Dosage] Treatment should be carried out in a special place (such as a hospital). Because patients have different sensitivities, a pilot injection should be given before regular treatment, and then the growth hormone secretion, carcinoid-related symptoms and tumor secretion should be observed. If the response is not sensitive, consider whether to implement this treatment. Acromegaly: A method of administration of a sustained-release dosage form, which can be initially administered intramuscularly once every 14 days, one at a time. Growth hormone and IGF-1 levels were assessed (measured prior to the next injection) and if the treatment response is not considered significant, it can be increased to 1 injection every 10 days. Carcinoid: A method of administration of a sustained-release dosage form, which can be initially administered intramuscularly once every 14 days, one at a time. After evaluating the clinical symptoms (facial flushing, soft stool), if the treatment response is not significant, it can be increased to 1 injection every 10 days.

    [Storage] Somatuline Depot must be stored in a refrigerator at 2 ° C to 8 ° C (36 ° F to 46 ° F) and protect the light in its original packaging. Thirty (30) minutes before the injection, the sealed Somatuline Depot bag was removed from the refrigerator and allowed to reach room temperature. Keep the bag sealed until it is injected.

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

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