Lapatinib

【Product name】Tykerb

[English common name]Lapatinib

[Chinese common name]Lapatinib

[English name]4-Quinazolinamine, lapatinib ditosylate monohydrate, GSK572016

[Chinese other name]Lapatinib base, lapatinib dimethanesulfonate intermediate, lapatinib monomer

[Indications] TYKERB lapatinib is used in combination with capecitabine for the treatment of ErbB-2 overexpression, and has previously received advanced or metastatic treatment including anthracyclines, paclitaxel, and trastuzumab (Herceptin).Breast cancer.

[Usage and Dosage] The recommended dose is 1 250 mg once a day, taken on the 1st to 21st day, combined with capecitabine 2 000 mg/d, and taken in 1 to 14 days. Lapatinib should be taken once a day. It is not recommended to take it in divided doses. Take 1 h before meals or 2 h after meals. If one dose is missed, the dose will not be doubled on the second day. Pregnancy level D, pregnant women are banned. It is unclear whether milk secretion is passed, and lactating women should stop breastfeeding. There were no significant differences between the elderly and young patients. Patients with severe kidney damage and dialysis have not been clinically tested, and patients with moderate to severe liver damage should be given a dose reduction.

[Storage] Do not store above 30oC.

[Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

说明书

各国版本

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中文学术

2015版《中国抗癌协会乳…规范》_药物治疗策略的解读_王碧芸

Her2阳性乳腺癌的精准治疗及研究进展_朱逸慜

LC-MS_MS法测定乳腺癌患者血浆中拉帕替尼浓度

SRT联合拉帕替尼治疗HE…乳腺癌脑转移疗效及预后分析_罗波

乳腺癌拉帕替尼耐药模型建立…双胍逆转其耐药性的初步探讨_王婷

吡咯替尼治疗HER-2阳性乳腺癌研究进展_谭玲珍

复方苦参注射液联合拉帕替尼…癌疗效及对肿瘤标志物的影响_秦海运

拉帕替尼与卡培他滨对HER…腺癌患者的疗效与安全性分析_王素娥

拉帕替尼治疗HER-2阳性转移性乳腺癌的临床效果_曾加佳

拉帕替尼治疗HER2阳性转移性乳腺癌的疗效和安全性_严颖

拉帕替尼联合曲妥珠单抗治疗…ER2阳性乳腺癌的疗效观察_夏秀林

拉帕替尼治疗晚期转移性乳腺癌的国内外研究进展_余宗艳

曲妥珠单抗和拉帕替尼在辅助曲妥珠单抗治疗后一线复发的HER2阳性晚期乳腺癌治疗中疗效的比较

曲妥珠单抗治疗失败的HER…疗方案的疗效及影响因素分析_张进儒

真实世界吡咯替尼治疗HER2阳性转移性乳腺癌的疗效及安全性

紫杉醇联合拉帕替尼治疗HE…2阳性晚期乳腺癌的疗效分析_张军峰

 

 

中文资讯

英文学术

英文资讯

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