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  Non-myeloid malignancy

  TBO-cell colony stimulating factor

  【Product name】Granix

  [English common name]Tbo-filgrastim

  [Chinese common name]TBO-Fogstone

  [English name]

  [Chinese other name]

  [indications]
  Recombinant human granulocyte colony-stimulating factor injection:
  1. Cancer chemotherapy and other reasons lead toNeutropeniaCancer patients use myelosuppressive chemotherapy drugs, especially after strong bone marrow deprivation chemotherapy, injection of this product can help prevent the occurrence of neutropenia, reduce the degree of neutropenia, shorten the granulocyte The duration of the deficiency accelerates the recovery of granulocyte counts, thereby reducing the risk of fever associated with infection.
  2. Promote an increase in the number of neutrophils after bone marrow transplantation.
  3. Neutropenia caused by myelodysplastic syndrome, neutropenia caused by aplastic anemia, congenital, idiopathic neutropenia, myelodysplastic syndrome with neutral Agranulocytopenia, periodic neutropenia.
  TBO-granulocyte colony-stimulating factor pre-filled syringe: GRANIX (TBO-granulocyte colony-stimulating factor) is a clinically significant anti-myeloablative disease with the incidence of myelosuppression with febrile neutropenia The duration of severe neutropenia in cancer drugs is indicative of leukocyte growth factor.

  【Dosage】
  Recombinant human granulocyte colony-stimulating factor injection: The product is administered subcutaneously or intravenously 24 to 48 hours after the end of administration of the chemotherapy drug, once a day. The dosage and time of administration of this product should be determined according to the intensity of chemotherapy and the degree of neutrophil decline. For patients with greater chemotherapy intensity or decreased granulocyte count, it is more suitable to continue to take the drug for more than 7 days at a dose of 2.5 μg/kg body weight/day until the neutrophil is restored to 5000/mm3; if the dose of chemotherapy drug is used Lower, estimated to cause less severe myelosuppression, consider using a lower dose to prevent neutropenia, 1.25μg / kg body weight / day dose to the neutrophil number is stable in a safe range, Patients with significantly reduced neutrophils after chemotherapy (neutrophil count <1000/mm3).
  TBO-granulocyte colony stimulating factor prefilled syringe:
  Recommended dose: 5 micrograms per kilogram per day for subcutaneous injection.
  Myelosuppressive chemotherapy was administered no earlier than 24 hours after the first dose was administered. Do not give chemotherapy for the first 24 hours.

  [Storage]
  Recombinant human granulocyte colony-stimulating factor injection: sealed and preserved.

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