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  Malignant mesothelioma

  Chimeric immunoglobulin G-1-κ monoclonal antibody

  【Product name】

  [English common name]IgG1/κ monoclonal antibody

  [Chinese common name]Chimeric immunoglobulin G-1-κ monoclonal antibody

  [English name]

  [Chinese other name]

  [Indications] Muckle-Wells syndrome (MWS), neonatal multisystem inflammatory disease (NOMID)

  [Usage and Dosage] For patients with CAPS, the recommended starting dose of Ilaris is: adults, adolescents and children ≥ 4 years old: 150 mg body weight > 40 kg patients _2 mg / kg body weight ≥ 15 kg patients, ≤ 40 kg _ 4 mg / kg body weight ≥ 7.5 kg and <15kg children. 2 to <4 years old: 4 mg/kg for patients weighing ≥ 7.5 kg. Subcutaneous injections are administered once every 8 weeks. For patients with a starting dose of 150 mg or 2 mg/kg, if the clinical response is satisfactory (the rash and other systemic inflammations are resolved), the conservative treatment symptoms are still not achieved 7 days after the start of treatment, and can be considered at 150 mg or 2 mg/kg. The second dose of Ilaris. If a complete therapeutic response is subsequently reached, an intensive dosing regimen of 300 mg or 4 mg/kg every 8 weeks should be maintained. If a satisfactory clinical effect is not obtained after 7 days of increasing dose, the third dose of Ilarisi 300 mg or 4 mg/kg can be considered. If a complete treatment response is followed, maintain an intensive dosing regimen of 600 mg or 8 mg/kg. According to individual clinical judgment, 8 weeks should be considered. For patients with a starting dose of 4 mg/kg, 8 weeks should be considered if a satisfactory clinical response is not obtained. The second dose of Ilylis 4 mg/kg can be considered 7 days after the start of treatment. If completely treated. A response was subsequently obtained, maintaining a booster dose regime of 8 mg/kg

  [Storage]

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