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  Acute T cell lymphoblastic leukemia , Lymphoma

  Nairabin

  【Product name】Arranon

  [English common name]Nelarabine

  [Chinese common name]Nairabin

  [English name]Nelzarabine [USAN]

  [Chinese other name]Nairabine intermediate

  [indications]
  Nairabin injection: used to relapse or not respond to drugs after at least two chemotherapy treatmentsT cell acute lymphoblastic leukemiawithT cell lymphomapatient.
  Nairabine injection: ARRANON is a nucleoside metabolism inhibitor for the treatment of patients with T-cell acute lymphoblastic leukemia and T-cell lymphoma whose disease does not respond or recur after treatment with at least two chemotherapy regimens. This use is based on the induction of complete reactions. Randomized trials demonstrating increased survival or other clinical benefits have not been performed.

  【Dosage】
  Nairabin injection: adult recommended dose of 1500 mg / m2, intravenous infusion for 2 hours, 21 days for a course of treatment, administered on days 1, 3, 5, without dilution.
  The recommended dose for children is 650 mg/m2, intravenous infusion for 1 hour, 21 days for one course of treatment, continuous infusion for 5 days without dilution.
  Nairabine injection: Adult dose: 1,500 mg/m2, intravenously every 21 days for 2 hours on days 1, 3 and 5.
  Pediatric dose: 650 mg/m2, intravenous injection for 1 hour per day for 5 consecutive days, repeated every 21 days.

  [Storage]Store Arranon injection at 25oC (77oF); Allows offsets from 15oC to 30oC (59oF to 86oF).

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