Showing all 8 results

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  Lennox-Gastaut syndrome , epilepsy

  Lufinamide

  【Product name】BANZEL

  [English common name]Rufinamide

  [Chinese common name]Lufinamide

  [English name]

  [Chinese other name]

  Indications syndromeepilepsyAdjuvant therapy for seizures.

  [Usage and Dosage] Initially 400-800mg per day, increase by 400-800mg / day every other day, reaching the goal of 3200mg / day. Avoid sudden stops (25% reduction every 2 days).

  [Storage] Store tablets at 25 ° C (77 ° F); allow for offset 15 ° -30 ° C (59 ° F – 86 ° F). Moisture proof. Replace the cover after opening.

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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  Lennox-Gastaut syndrome

  Lamotrigine

  [Product Name]Lamictal

  [English common name] Lamotrigine

  [Chinese common name] Lamotrigine

  [Other names in English] 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine

  [Chinese other name] Lamicot

  [Indications]
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  Lennox-Gastaut syndrome

  Ferric ester

  【Product name】Felbatol

  [English common name]Felbamate

  [Chinese common name]Ferric ester

  [English name]W 554, Felbamatum [Latin]; Felbatol

  [Chinese other name]Non-urethane, non-Bammat

  [indications]
  1. Single or adjuvant therapy for or without systemic seizuresepilepsyPartial seizures.
  2. Also available forLennox-Gastaut syndromeAuxiliary treatment.

  【Dosage】Conventional adult dose
  The initial dose for oral administration is 1.2g per day, taken in 3-4 times, and can be increased by 0.6-1.2g every 1-2 weeks. The usual dose is 2.4-3.6g per day.
  Child's regular dose
  Oral administration of Lennox-Gastaut syndrome (supplemented with other antiepileptic drugs): children aged 2-14 years, 15mg/kg a day, 3-4 times orally, 15mg/kg every other week, the maximum daily dose is 45mg/kg. Children over the age of 14 use the same amount as adults.
  Foreign usage and usage reference
  Oral administration of adult episodes of partial seizures:
  (1) The drug is treated with a single dose of 1.2 g per day, taken in 3-4 times. After the increase of 0.6g every 2 weeks, it can be increased to 2.4g a day, if necessary, up to 3.6g a day, in divided doses.
  (2) The conversion from the combination to the single use of the drug, the initial dose of the drug is 1.2g a day, divided into 3-4 times, while other anti-epileptic drugs are reduced by 1/3; the second week of the drug increased to one day 2.4g, divided into 3-4 times, other anti-epileptic drugs reduced by 1/3; in the third week, the drug increased to 3.6g a day, divided into 3-4 times, other drugs continue to reduce to stop.
  (3) The drug is used as an auxiliary drug for the treatment of partial seizures of epilepsy. The initial dose is 1.2g per day, divided into 3-4 times. At the same time, other antiepileptic drugs are reduced by 20%. After that, other drugs are gradually reduced to the minimum dose. The drug is dosed at a dose of 1.2g per week, and the maximum dose is up to 3.6g per day, taken in divided doses.
  In patients with renal insufficiency, the dose of renal dysfunction should be adjusted according to renal function.
  The dosage of elderly patients in the elderly is reduced.
  Child's regular dose
  Oral administration of Lennox-Gastaut syndrome: as an adjuvant, children aged 2-14 years, 15mg/kg a day, divided into 3-4 times, while other antiepileptic drugs are reduced by 20%; thereafter, a dose of 15mg/kg a week Increasing, up to the maximum dose of 45mg/kg a day, other drugs continue to reduce to the least adverse reactions. Children over the age of 14 use the same amount as adults.

  [Storage]20-25 ° C sealed storage

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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  Lennox-Gastaut syndrome , Infant severe myoclonic epilepsy (Dravet syndrome)

  Valproic acid

  【Product name】DEPACON, DEPAKENE, VALERIN

  [English common name]Valproic Acid

  [Chinese common name]Valproic acid

  [English name]Mylproin, Ergenyl

  [Chinese other name]2-propyl valeric acid, A-propyl valeric acid

  [indications]
  Sodium valproate for injection: This product is used for treatmentepilepsyIn adults and children, when it is temporarily not possible to take oral dosage forms, it is used to replace oral dosage forms.
  Sodium valproate sustained-release tablets: for the treatment of systemic and partial seizures, as well as special types of syndromes.
  1. Systemic epilepsy applies to: absence seizures, myoclonic seizures, tonic-clonic seizures, tonic seizures, and mixed seizures.
  2. Partial epilepsy applies to: simple partial seizures; complex partial seizures; partial secondary systemic seizures.
  3. Special type syndrome: West,Lennox-Gastaut syndrome.

  【Dosage】
  Sodium valproate for injection: for temporary replacement (for example, waiting for surgery): intravenous administration after 4 to 6 hours of oral administration, the intravenous injection of this product is dissolved in 0.9% normal saline, or continuous intravenous infusion over 24 Intravenous infusions are administered four times a day, or over a maximum dose range (usually an average dose of 20 to 30 mg/kg/day), for more than one hour each time. Need to quickly reach the effective blood concentration and maintain: slow intravenous bolus injection at a dose of 15mg / kg, more than 5 minutes; then intravenously drip at a rate of 1mg / kg / hr, so that the plasma sodium valproate concentration reached 75mg / L, and Adjust the infusion rate according to the clinical situation. Once the intravenous infusion is stopped, it should be administered orally immediately to supplement the active ingredient. The oral dose can be used in the previous or adjusted dose, or as directed.
  Sodium valproate sustained-release tablets: The daily dose should be determined according to the age and weight of the patient, and the wide individual sensitivity to valproic acid should be considered. The relationship between daily dose, serum concentration and efficacy has not been established. The optimal dose should be determined according to the clinical response: when the seizure cannot be controlled or suspected to have side effects, in addition to clinical monitoring, the determination of the plasma concentration of sodium valproate should be considered. The effective range has been reported to be 40-100 mg/l ( 300-700 μmol/l).
  1. Initial treatment administration method (oral):
  (1) In patients who did not receive other antiepileptic drugs, the drug dose was increased every 2-3 days, and the optimal dose was reached within 1 week.
  (2) In patients who have previously received other anti-epileptic drugs, this product should slowly increase the dose and reach the optimal dose within 2 weeks.

  [Storage]
  Sodium valproate for injection: sealed.
  Sodium valproate sustained-release tablets: sealed and placed in a cool place.

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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  Lennox-Gastaut syndrome , Infant severe myoclonic epilepsy (Dravet syndrome)

  Sodium valproate

  【Product name】VALPROIC, Depacon

  [English common name]Sodium Valproate

  [Chinese common name]Sodium valproate

  [English name] sodium, 2-propylpentanoate

  [Chinese other name]Sodium 2-propylvalerate

  [indications]
  Sodium valproate tablets: mainly used for simple or complex absence seizures, myoclonic seizures, large seizures of single or combined medications, and sometimes have a certain effect on complex partial seizures.
  Sodium valproate syrup: This product is used for systemic, partial or other types.epilepsy.

  【Dosage】
  Sodium valproate tablets:
  Adults commonly used: daily weight 15mg / kg or 0.6-1.2g (3-6 tablets) per day 2-3 times. Start with 5-10mg/kg, and increase it after one week until it can control the seizure. When the daily dosage exceeds 250mg, it should be taken in divided doses to reduce gastrointestinal irritation. The maximum daily dose is no more than 30mg/kg by weight, or 1.8-2.4g (9-12 pieces) per day. Commonly used in children: the same as adults, can also be 20-30mg/kg per day, divided into 2-3 times or 15mg/kg per day, increase by 5-10mg/kg every other week, to be effective or not Tolerance.
  Sodium valproate syrup: Oral:
  1 Adult commonly used amount: daily weight 15mg/kg or 600~1200mg daily, in divided doses. At the beginning, the body weight is 5-10 mg/kg, and it increases after one week until the seizure is controlled. When the daily dosage exceeds 250mg, it should be taken in divided doses daily to reduce gastrointestinal irritation. The maximum amount is generally not more than 30 mg/kg per day, or 1.8 to 2.4 g per day.
  2 pediatric commonly used amount: the same as adults by weight. It has also been reported that at the beginning, the body weight is 15 mg/kg, and 5 to 10 mg/kg is added every other week as needed until it is effective or not tolerated.

  [Storage]
  Sodium valproate tablets: sealed and stored in a dry place.
  Sodium valproate syrup: shading, sealed, and kept in a cool dry place.

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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  Lennox-Gastaut syndrome , Infant severe myoclonic epilepsy (Dravet syndrome)

  Topiramate

  【Product name】TOPINA

  [English common name]Topiramate

  [Chinese common name]Topiramate

  [English name]Topmatt

  [Chinese other name]Topemat

  [Indications] This product is used for single-drug treatment of patients with newly diagnosed epilepsy or once combined with medication is now converted to monotherapyepilepsypatient. This product is used for the treatment of partial seizures in adults and children aged 2 to 16 years.

  [Usage and Dosage] It is recommended to start treatment from low doses in adults and children, and then gradually increase the dose to adjust to the effective dose. Do not smash the tablets. This product is effective in treating partial seizures in adults and children. In the control treatment trials, it has been confirmed that the plasma concentration of topiramate has no correlation with clinical efficacy. There is no evidence that topiramate is tolerated in humans, and dose-ranging studies in patients with partial seizures in adults have shown that doses greater than 400 mg/day (600, 800, and 1000 mg/day) do not increase efficacy. When using this product, it is not necessary to monitor the plasma topiramate concentration for optimal efficacy. When this product is added with phenytoin, only a very small number of cases need to adjust the dosage of phenytoin to achieve the best clinical efficacy.

  [Storage] Sealed.

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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  Lennox-Gastaut syndrome , Familial spastic paraplegia

  Clonazepam

  【Product name】Rivotril

  [English common name]Clonazepam

  [Chinese common name]Clonazepam

  [English name]Clonazepam methanol solution

  [Chinese other name]Clonazepam

  [indications]
  Clonazepam injection: mainly used to control various typesepilepsyEspecially suitable for the absence of seizures,Infantile spasm,MyoclonicInsufficiency of exercise andLennox-Gastaut syndrome.
  Clonazepam tablets: This product is mainly used to control various types of epilepsy, especially for absence seizures, infantile spasms, myoclonic, motor insufficiency and Lennox-Gastaut syndrome.

  【Dosage】
  Clonazepam injection: The dosage should be individualized according to the specific conditions of the patient, and the intramuscular injection should be avoided as much as possible. The epileptic state can be controlled by intravenous injection. The adult dose is 1-4mg, and the injection is completed slowly in about 30 seconds. If the continuous state is still uncontrolled, the original dose can be repeated 1 or 2 times every 20 minutes. The maximum amount for adults is no more than 20 mg per day.
  Clonazepam tablets:
  1. The amount commonly used in adults: start with 0.5mg each time, 3 times a day, increase 0.5-1mg every 3 days, until the seizure is controlled or adverse reactions occur: the dosage should be individualized, the maximum amount of adults should not exceed 20mg per day. .
  2. Commonly used in children: children aged 10 years old or younger than 30kg start to take 0.01~0.03mg/kg per day, take 2~3 times, then increase 0.25~0.5mg every 3 days, to reach 0.1% by weight per day. ~0.2mg/kg or an adverse reaction has occurred.
  3. The course of clonazepam should not exceed 3 to 6 months.

  [Storage]
  Clonazepam injection: shading, confined preservation.
  Clonazepam tablets: sealed and preserved.

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.
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  Lennox-Gastaut syndrome , Infant severe myoclonic epilepsy (Dravet syndrome)

  Chlorba

  【Product name】Onfi

  [English common name]Clobazam

  [Chinese common name]Chlorba

  [English name]1H-1

  [Chinese other name]Oxygen and stability

  [indications]Suitable for anxiety and refractoryepilepsyTreatment. It is more effective for epileptic seizures followed by systemic seizures and Lun-Plus syndrome.

  【Dosage】
  1. Commonly used 20 ~ 30mg per day, divided into clothes, or a single evening service.
  2. Auxiliary treatment for epilepsy: dose and usage are the same as treatment of anxiety.
  Children 3.3 years of age or older: The recommended dose is no more than 1/2 of the adult dose.
  4. The recommended dose for elderly or infirm patients is 10 to 20 mg per day.

  [Storage] Store at 20-25 ° C (68-77 ° F).

  [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.