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  • Gaucher disease

    Imiglucerase

    【Product name】Cerezyme

    [English common name]Imiglucerase

    [Chinese common name]Imiglucerase

    [English name]Cerezyme

    [Chinese other name]Brain enzyme

    [indications]Gaucher diseaseSymptom improvement (anemia,Thrombocytopenia, hepatosplenomegaly and skeletal symptoms).

    【Dosage】As an immunoglucanase (genetic recombination), 60 units/kg body weight is infused every other week for 1 to 2 hours, or an appropriate dose is administered at an infusion rate of no more than 1 unit/kg/min.
    For dosing, 1 vial was dissolved in 10.2 mL of water for injection and 10.0 mL was collected per vial. The desired amount of chemical solution is diluted with physiological saline to a final volume of 100-200 ml.
    Incidentally, it should be increased or decreased depending on the degree of symptoms.
    Further, after a period of administration, the therapeutic effect is judged, and when a sustained improvement state is observed, the maintenance dose can be reduced from the initial amount. The treatment effect can be carefully observed and the body weight can be further reduced at intervals of 3 to 6 months.

    [Storage]Store at 2-8 °C in the dark.

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