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  • Lennox-Gastaut syndrome , Infant severe myoclonic epilepsy (Dravet syndrome)

    Valproic acid

    【Product name】DEPACON, DEPAKENE, VALERIN

    [English common name]Valproic Acid

    [Chinese common name]Valproic acid

    [English name]Mylproin, Ergenyl

    [Chinese other name]2-propyl valeric acid, A-propyl valeric acid

    [indications]
    Sodium valproate for injection: This product is used for treatmentepilepsyIn adults and children, when it is temporarily not possible to take oral dosage forms, it is used to replace oral dosage forms.
    Sodium valproate sustained-release tablets: for the treatment of systemic and partial seizures, as well as special types of syndromes.
    1. Systemic epilepsy applies to: absence seizures, myoclonic seizures, tonic-clonic seizures, tonic seizures, and mixed seizures.
    2. Partial epilepsy applies to: simple partial seizures; complex partial seizures; partial secondary systemic seizures.
    3. Special type syndrome: West,Lennox-Gastaut syndrome.

    【Dosage】
    Sodium valproate for injection: for temporary replacement (for example, waiting for surgery): intravenous administration after 4 to 6 hours of oral administration, the intravenous injection of this product is dissolved in 0.9% normal saline, or continuous intravenous infusion over 24 Intravenous infusions are administered four times a day, or over a maximum dose range (usually an average dose of 20 to 30 mg/kg/day), for more than one hour each time. Need to quickly reach the effective blood concentration and maintain: slow intravenous bolus injection at a dose of 15mg / kg, more than 5 minutes; then intravenously drip at a rate of 1mg / kg / hr, so that the plasma sodium valproate concentration reached 75mg / L, and Adjust the infusion rate according to the clinical situation. Once the intravenous infusion is stopped, it should be administered orally immediately to supplement the active ingredient. The oral dose can be used in the previous or adjusted dose, or as directed.
    Sodium valproate sustained-release tablets: The daily dose should be determined according to the age and weight of the patient, and the wide individual sensitivity to valproic acid should be considered. The relationship between daily dose, serum concentration and efficacy has not been established. The optimal dose should be determined according to the clinical response: when the seizure cannot be controlled or suspected to have side effects, in addition to clinical monitoring, the determination of the plasma concentration of sodium valproate should be considered. The effective range has been reported to be 40-100 mg/l ( 300-700 μmol/l).
    1. Initial treatment administration method (oral):
    (1) In patients who did not receive other antiepileptic drugs, the drug dose was increased every 2-3 days, and the optimal dose was reached within 1 week.
    (2) In patients who have previously received other anti-epileptic drugs, this product should slowly increase the dose and reach the optimal dose within 2 weeks.

    [Storage]
    Sodium valproate for injection: sealed.
    Sodium valproate sustained-release tablets: sealed and placed in a cool place.

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

  • Infant severe myoclonic epilepsy (Dravet syndrome)

    Cannabisdiol

    [product name] CBDOIL

    [English common name]Cannabidiol

    [Chinese common name]Cannabisdiol

    [English name]CANNABIDIOL

    [Chinese other name]Cannabinol

    [Indications] EPIDIOLEX is suitable for the treatment of patients 2 years old and olderLennox-Gastaut syndromeorDravet syndromerelatedepilepsyattack.

    【Dosage】
    The recommended starting dose is 2.5 mg / kg twice daily (5 mg / kg / day). After one week, the dose can be increased to a maintenance dose of 5 mg / kg twice daily (10 mg / kg / day).
    Based on individual clinical response and tolerability, EPIDIOLEX can be increased to a maximum recommended maintenance dose of 10 mg / kg twice daily (20 mg / kg / day).

    [Storage] 2-8 ° C.

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

  • Lennox-Gastaut syndrome , Infant severe myoclonic epilepsy (Dravet syndrome)

    Sodium valproate

    【Product name】VALPROIC, Depacon

    [English common name]Sodium Valproate

    [Chinese common name]Sodium valproate

    [English name] sodium, 2-propylpentanoate

    [Chinese other name]Sodium 2-propylvalerate

    [indications]
    Sodium valproate tablets: mainly used for simple or complex absence seizures, myoclonic seizures, large seizures of single or combined medications, and sometimes have a certain effect on complex partial seizures.
    Sodium valproate syrup: This product is used for systemic, partial or other types.epilepsy.

    【Dosage】
    Sodium valproate tablets:
    Adults commonly used: daily weight 15mg / kg or 0.6-1.2g (3-6 tablets) per day 2-3 times. Start with 5-10mg/kg, and increase it after one week until it can control the seizure. When the daily dosage exceeds 250mg, it should be taken in divided doses to reduce gastrointestinal irritation. The maximum daily dose is no more than 30mg/kg by weight, or 1.8-2.4g (9-12 pieces) per day. Commonly used in children: the same as adults, can also be 20-30mg/kg per day, divided into 2-3 times or 15mg/kg per day, increase by 5-10mg/kg every other week, to be effective or not Tolerance.
    Sodium valproate syrup: Oral:
    1 Adult commonly used amount: daily weight 15mg/kg or 600~1200mg daily, in divided doses. At the beginning, the body weight is 5-10 mg/kg, and it increases after one week until the seizure is controlled. When the daily dosage exceeds 250mg, it should be taken in divided doses daily to reduce gastrointestinal irritation. The maximum amount is generally not more than 30 mg/kg per day, or 1.8 to 2.4 g per day.
    2 pediatric commonly used amount: the same as adults by weight. It has also been reported that at the beginning, the body weight is 15 mg/kg, and 5 to 10 mg/kg is added every other week as needed until it is effective or not tolerated.

    [Storage]
    Sodium valproate tablets: sealed and stored in a dry place.
    Sodium valproate syrup: shading, sealed, and kept in a cool dry place.

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

  • Lennox-Gastaut syndrome , Infant severe myoclonic epilepsy (Dravet syndrome)

    Topiramate

    【Product name】TOPINA

    [English common name]Topiramate

    [Chinese common name]Topiramate

    [English name]Topmatt

    [Chinese other name]Topemat

    [Indications] This product is used for single-drug treatment of patients with newly diagnosed epilepsy or once combined with medication is now converted to monotherapyepilepsypatient. This product is used for the treatment of partial seizures in adults and children aged 2 to 16 years.

    [Usage and Dosage] It is recommended to start treatment from low doses in adults and children, and then gradually increase the dose to adjust to the effective dose. Do not smash the tablets. This product is effective in treating partial seizures in adults and children. In the control treatment trials, it has been confirmed that the plasma concentration of topiramate has no correlation with clinical efficacy. There is no evidence that topiramate is tolerated in humans, and dose-ranging studies in patients with partial seizures in adults have shown that doses greater than 400 mg/day (600, 800, and 1000 mg/day) do not increase efficacy. When using this product, it is not necessary to monitor the plasma topiramate concentration for optimal efficacy. When this product is added with phenytoin, only a very small number of cases need to adjust the dosage of phenytoin to achieve the best clinical efficacy.

    [Storage] Sealed.

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

  • Constitutional liver dysfunction jaundice (Gilbert syndrome) , Arterial liver dysplasia syndrome

    Phenobarbital

    【Product name】Lumina, HYDANTOL, PHENOBAL

    [English common name]Phenobarbital

    [Chinese common name]Phenobarbital

    [English name]Phenobasone

    [Chinese other name]Phenobarbital

    [indications]
    Compound phenobarbital sodium bromide tablets: calming the mind, relieving phlegm and calming. For all typesepilepsyWith neurosis.
    Phenolbarbital scopolamine tablets: used to control symptoms of motion sickness such as dizziness, nausea and vomiting caused by riding, boat and aircraft.
    Phenobarbital tablets: This product is mainly used to treat anxiety, insomnia (for patients with short sleep time), epilepsy and movement disorders. It is an important drug for the treatment of epileptic seizures and localized seizures. It can also be used as an anti-hyperbilirubinemia drug and before anesthesia.
    Phenobarbital sodium injection: This product is effective for the treatment of epilepsy, both systemic and partial seizures, generallyPhenytoin, carbamazepine,Sodium valproateUse when invalid. It can also be used for convulsions and pre-anesthesia administration caused by other diseases.

    【Dosage】
    Compound phenobarbital sodium bromide tablets: Oral, 1-2 tablets at a time, 2-3 times a day.
    Phenolbarbital scopolamine tablets: oral. Take 1 tablet at a time and take it 20 minutes before the ride.
    Phenobarbital tablets: commonly used in adults: hypnosis, 30 ~ 100mg, once a night service; calm, once 15 ~ 30mg, 2 or 3 times a day; anticonvulsant, daily 90 ~ 180mg, can be served at night , or 30 ~ 60mg each time, three times a day; a maximum amount of 250mg, 500mg a day; anti-hyperbilirubinemia, once 30 ~ 60mg, three times a day. Commonly used in children: medication should be individualized, sedative, each weight 2mg/kg, or body surface area 60mg/m2, 2 to 3 times a day; anticonvulsant, each weight 3 ~ 5mg / kg; anti-biliary Redness, each time according to the weight of 5 ~ 8mg / kg, divided into oral, 3 to 7 days effective.
    Sodium phenobarbital injection: intramuscular injection: anticonvulsant and status epilepticus, adult 100 ~ 200mg once, if necessary, can be repeated 4 to 6 hours. Pre-anesthesia administration: intramuscular injection of 100-200 mg 0.5 to 1 hour before surgery.

    [Storage]
    Compound phenobarbital sodium bromide tablets: sealed and kept in a cool dry place.
    Phenolbarbital scopolamine tablets: sealed and preserved.
    Phenobarbital tablets: sealed.
    Sodium phenobarbital injection: sealed, stored in a cool dark place (not to exceed 20 ° C in the dark).

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

  • Infant severe myoclonic epilepsy (Dravet syndrome)

    Levetiracetam

    【Product name】Kaipulan

    [English common name]Levetiracetam

    [Chinese common name]Levetiracetam

    [English name](s)-2-(2-oxopyrrolidin-1-yl)butanamide

    [Chinese other name](S)-alpha-ethyl-2-oxo-1-acetamide pyrrolidine

    [indications]For adults and children over 4 years oldepilepsyThe patient is treated with partial seizures.

    【Dosage】
    1. Route of administration: Oral. It should be swallowed with an appropriate amount of water and taken without being affected by eating.
    2. Method of administration and dosage Adults (>18 years old) and adolescents (12-17 years old) weighing ≥50 kg The initial therapeutic dose is 500 mg each time, twice a day. Based on clinical efficacy and tolerability, the daily dose can be increased to 1500 mg each time, twice daily. The change in dose should be increased or decreased by 500 mg/time every 2-4 weeks. 2 times a day. The elderly (≥65 years old) adjusted the dose according to the renal function (see below for description of patients with impaired renal function). Children and adolescents aged 4-11 (12-17 years old) weighing ≤ 50 kg The initial therapeutic dose is 10 mg/kg twice daily.

    [Storage]Store at room temperature (25 ° C or below).

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content..

  • Infant severe myoclonic epilepsy (Dravet syndrome)

    Dioxenol

    【Product name】DIACOMIT

    [English common name]Stiripentol

    [Chinese common name]Dioxenol

    [English name]

    [Chinese other name]

    [indications]Severe myoclonic epilepsy in infants(Dravet syndrome),Dioxenol is effective in reducing the frequency of seizures in children.

    [Usage and Dosage] The recommended oral dose of DIACOMIT is 50 mg / kg / day, divided into 2 or 3 divided doses (ie 16.67 mg / kg three times daily or 25 mg / kg twice daily). If the exact dose cannot be reached at the available intensity, it is as close as possible to the nearest dose, usually in the range of 50 mg to 150 mg of the recommended 50 mg / kg / day. This dose can be achieved using a combination of two DIACOMIT intensities. The maximum recommended total dose is 3,000 mg/day.

    [Storage] Store at room temperature between 68 °F and 77 °F (20 °C to 25 °C).

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

  • Infant severe myoclonic epilepsy (Dravet syndrome)

    Potassium bromide

    【Product name】

    [English common name]Potassium bromide

    [Chinese common name]Potassium bromide

    [English name]Standard Liquid

    [Chinese other name]Standard solution

    [Indications] are often used in neurasthenia, rickets, neurological insomnia, and mental excitement.

    [Usage and Dosage] Oral, 10% solution 5-10ml, 3 times a day, served after meals.

    [Storage] sealed and protected from light.

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

  • Lennox-Gastaut syndrome , Infant severe myoclonic epilepsy (Dravet syndrome)

    Chlorba

    【Product name】Onfi

    [English common name]Clobazam

    [Chinese common name]Chlorba

    [English name]1H-1

    [Chinese other name]Oxygen and stability

    [indications]Suitable for anxiety and refractoryepilepsyTreatment. It is more effective for epileptic seizures followed by systemic seizures and Lun-Plus syndrome.

    【Dosage】
    1. Commonly used 20 ~ 30mg per day, divided into clothes, or a single evening service.
    2. Auxiliary treatment for epilepsy: dose and usage are the same as treatment of anxiety.
    Children 3.3 years of age or older: The recommended dose is no more than 1/2 of the adult dose.
    4. The recommended dose for elderly or infirm patients is 10 to 20 mg per day.

    [Storage] Store at 20-25 ° C (68-77 ° F).

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

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