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  • Coronary heart disease , Liver Disease

    Perfluoropropane lipid microspheres

    【Product name】Definity

    [English common name]Perflutren

    [Chinese common name]Perfluoropropane

    [English name]Perfluoropropane, Octafluoropropane, Perfluoropropaneminimum

    [Chinese other name]Octafluoropropane, perfluoropropane lipid microsphere suspension injection

    [indications]For the improvement of conventional echocardiography, the recognition of the left ventricular endocardial border is enhanced.

    【Dosage】Peripherally intravenous injection, the recommended dose is 0.01ml / kg each time.
    (1) Preparation of the drug: After the appearance of the test is qualified, the drug is mixed, and the force is not shaken to prevent the microsphere from rupturing and foaming. In order to keep the pressure constant so as not to break the microspheres, another injection needle should be inserted into the vial plug to pass the atmosphere to keep the pressure constant, and then the suspension is sucked into the syringe.
    (2) Drug injection: The patient takes the left lateral position (for echocardiography), and inserts the hair needle with the tee into the dorsal vein of the right upper limb or the median vein of the elbow. Use a 10 ml syringe to extract 10 ml of 0.9% sodium chloride injection to the end of the tee, and use a 1 ml or 2 ml syringe to extract the mixed perfluoropropane human albumin microsphere injection to the other end of the tee to about 1 ml/sec. The injection speed bolus, then with a 0.9% sodium chloride injection 5 ~ 10ml bolus to make the contrast agent in the tube all into the blood circulation, complete the ultrasound examination during the injection process. If the effect is not satisfactory, the injection dose can be increased to 0.02ml/kg for injection, but the total number of injections should not exceed 2 times.
    note:
    (1) Do not inject air into the bottle.
    (2) This product is required to reach room temperature before use.
    (3) If the appearance is unqualified and the rubber stopper is damaged, please do not use it; use it immediately after opening; if the product is fully mixed, the solution is clear and not evenly white, indicating that the microsphere may have been destroyed. Will cause the ultrasound contrast effect to be poor or disappear, please do not use; if the drug has foreign matter or precipitate, do not use. The time interval between mixing the liquid and refraction should not exceed 1 minute. If it is more than 1 minute, invert the syringe and gently rotate to mix the microspheres. A pillow of size 20 or larger should be inserted into the peripheral vein before injection. Do not use a syringe to draw blood before injecting this product to avoid clot formation in the syringe.

    [Storage]Refrigerate and store at 2-8 °C in the dark. Do not invert and shake vigorously. Freezing is strictly prohibited.

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.