【Product name】Stelara
[English common name]Ustekinumab
[Chinese common name]Utec monoclonal antibody
[English name]
[Chinese other name]
[Indications] Stelara is a drug used to treat the following diseases:
Moderate to severe plaque psoriasis (a disease that causes red, scaly plaque in the skin). It is used in adults and children over the age of 12, and its condition is unresponsive or cannot be treated with other systemic (systemic) psoriasis, such as cyclosporine, methotrexate or PUVA (psoralen UV A). PUVA is a treatment in which a patient receives a drug containing a compound called "psoralen" prior to exposure to ultraviolet light.
Activity in adultsPsoriatic arthritis(Inflammation of the joints associated with psoriasis), when the condition is not adequately responsive to other treatments, is called anti-rheumatic drugs (DMARDs) that improve the disease. Stelara can be used alone or in combination with methotrexate (DMARD); moderate to severe activity in adultsCrohn's disease(a disease that causes intestinal inflammation), whose condition is poorly responsive to other Crohn's disease treatments or is unacceptable for such treatment.
[Usage and Dosage] Adults aged 18 years and older started treatment with a loading dose of 320 mg delivered to two 2 ml, subcutaneously 160 mg on the same day at two different locations. Continue to use a weekly injection of 160 mg as a single, 2 ml, subcutaneously administered dose. Don't give ARCALYST more often than once a week. Pediatric patients are 12 to 17 years old: the starting dose for treatment is 4.4 mg/kg, up to 320 mg, delivered with one or two subcutaneous injections, with a maximum single injection volume of 2 mL. Continue to administer a weekly injection of 2.2 mg/kg, up to 160 mg, as a single subcutaneous injection, up to 2 ml. If the initial dose given is two injections, they should be on the same day at two different locations. Don't give ARCALYST more often than once a week.
[Storage] Store in the refrigerator (2 ° C – 8 ° C). Do not freeze. Keep the vial in an outer carton to prevent light from shining.
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