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  • Neutrophil reduction

    Caspofungin acetate

    【Product name】Cancidas

    [English common name]Caspofunan

    [Chinese common name]Caspofungin acetate

    [English name]

    [Chinese other name]

    [Indications] This product is suitable for the treatment of Candida sepsis and the following Candida infections: abdominal abscess, peritonitis and abdominal infection; esophageal candidiasis; refractory or intolerable other treatments such as amphotericin B, amphotericin B Treatment of invasive aspergillosis of liposomal formulations and/or itraconazole. Also used for heat generationNeutropeniaTreatment of patients with fungal infections.

    【Dosage】
    1. Candida sepsis and other Candida infections: Adult dose is the first day load dose 70mg, followed by maintenance dose 50mg daily, slow intravenous infusion for 1h. The course of treatment depends on the patient's clinical and microbiological response, usually at least 14 days after the last blood culture is negative. Patients with neutropenia should be treated for a long period of time and continue until granulocyte recovery.
    2. Esophageal candidiasis: 50mg daily, slowly intravenously for 1h. Because HIV patients are prone to relapse, they can be treated with inhibition.
    3. Invasive aspergillosis: the first day load dose of 70mg, followed by a maintenance dose of 50mg daily, slowly intravenous infusion for 1h. The course of treatment depends on the severity of the patient's underlying disease, the recovery of the immune defect, and the clinical response.
    4. Renal dysfunction and mild liver dysfunction patients do not need to adjust the dose, the first day load dose of patients with moderate liver dysfunction is 70mg, followed by a maintenance dose of 35mg daily.
    5. When combined with efavirenz, nelfinavir, nefirapine, rifampicin, dexamethasone, phenytoin, carbamazepine, the first day load dose of 70mg, maintenance dose of 70mg daily.
    6. Solution preparation: Put the injection into the room temperature, add 10.5ml of water for injection or O.9% sodium chloride injection to dissolve the solution, the concentration is 7mg/ml (70mg per bottle) or 5mg/ml (per Bottle 50mg package); according to the dosage of the patient, take the appropriate amount of the dissolved solution into 0.9% sodium chloride injection or 250ml of lactated Ringer's injection to obtain a dilution for intravenous infusion.

    [Storage] Caspofungin injection: 50mg / support; 70mg / support. Refrigerate in a refrigerator at 2 to 8 °C. The dissolved solution of this product can be stored at 25 ° C for 1 h. The diluted intravenous solution can be stored in a refrigerator at 2-8 ° C for 48 h or 24 h at 25 ° C for 24 h.

    [Tips] Some of the information on this site comes from the Internet and is only used internally by pharmacists or medical staff. It is not a substitute for doctors to diagnose face to face. Please consult a professional pharmacist for specific medications. Please refer to the actual product manual or the actual product for the product content.

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