Mantle cell lymphoma
Ibrutinib
【Product name】Imbruvica
[English common name]Ibrutinib
[Chinese common name]Ibrutinib
[English name]Ibrutinib N-2, Ibrutinib intermeidate N-2, Ibrutinib INT1
[Chinese other name]Ibbutinib intermediate N-2, Ibrutinib intermediate, Ibrutinib intermediate N-2
[Indications] IMBRUVICA is a kinase inhibitor shown for the treatment of patients:
Who received at least one pre-treatmentMantle cell lymphoma (MCL).
Accelerate the approval of the overall response rate based on this indicator. This instruction continues to approve the clinical effectiveness validation team without a confirmatory trial.
Chronic lymphocytic leukemia (CLL).
Chronic lymphocyte leukemia17p is missing.
Waldenstrom's macroglobulinemia (WM).
[Usage and Dosage] MCL: 560 mg, once a day orally (4 capsules of 140 mg once daily).
CLL and WM: 420 mg once daily (third grade 140 mg capsule once daily).
Capsules should be taken orally in a glass of water. Do not open, rest, or chew capsules.
[Storage] Bottles are stored at room temperature between 20 ° C and 25 ° C (68 ° F to 77 ° F). The tour is allowed between 15 ° C and 30 ° C (59 ° F to 86 ° F). Keep the original packaging until dispensing.
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